The Nobel Prize Winning Discoveries in Infectious Diseases reviews all of the discoveries that have merited a Nobel Prize in the field of medical microbiology and infectious diseases. Each discovery is described in a separate chapter in terms suitable for the general reader.

The book is divided into sections according to the basic biological classification of the infectious agent and each section has an introductory chapter that surveys the essential features of that class. In each chapter, the origins and relationship of the findings to the general field are described and some speculations on further advances in the specific area are offered.

No other work provides a comprehensive and integrated survey of the entire subject.

About the Authors

David Rifkind received a PhD in microbiology at the University of California, Los Angeles and then an MD degree at the University of Chicago. He trained in internal medicine at the University of Colorado, Denver, and then in infectious diseases at the National Institute of Allergy and Infectious Diseases, NIH, USA. He has studied and published on viral and fungal respiratory diseases, the mechanism of action of bacterial endotoxins, the hormonal modulation of the immune response, and infectious disease in immune compromised organ transplant recipients, amongst others. He is the author of two books on internal medicine and pediatrics.

Geraldine L. Freeman received her MD degree at Stanford University School of Medicine, California, USA. She trained in pediatrics and in allergy/immunology. In addition, she holds an MS degree in statistics from the University of Arizona. She has studied and published on respiratory diseases in children and on the immune deficiency syndromes that predispose to infectious diseases.

"Rifkind and Freeman's account serves as an introduction for the general reader to microbiology, immunology and infectious diseases..."

- Robin A. Weiss, University College London for NATURE MEDICINE (June 2006)

"...provoke(s) reader thought regarding the never-ending process of scientific pursuit, and future candidates for Nobel Prizes."

- DOODY'S (3 Stars) 2006

"Rifkind and Freeman's account serves as an introduction for the general reader to microbiology, immunology and infectious diseases..."

- Robin A. Weiss, University College London for NATURE MEDICINE (June 2006)

"...provoke(s) reader thought regarding the never-ending process of scientific pursuit, and future candidates for Nobel Prizes."

- DOODY'S (3 Stars) 2006

"...provoke(s) reader thought regarding the never-ending process of scientific pursuit, and future candidates for Nobel Prizes."

- DOODY'S (3 Stars) 2006

Nobel Prizes."

- DOODY'S (3 Stars) 2006

. He is the author of two books on internal medicine and pediatrics.

Geraldine L. Freeman received her MD degree at Stanford University School of Medicine, California, USA. She trained in pediatrics and in allergy/immunology. In addition, she holds an MS degree in statistics from the University of Arizona. She has studied and published on respiratory diseases in children and on the immune deficiency syndromes that predispose to infectious diseases.

fectious diseases.

Preface

Acknowledgments

Introduction

Alfred Nobel and the Nobel Prizes

Immunity

Serotherapy

Antimicrobial Defenses

MHC Restriction

Antimicrobials

Prontosil and the Sulfonamides

Penicillin

Streptomycin

Chemotherapeutic Agents

Bacteria

Tuberculosis

Typhus

Syphilis Therapy

Viruses

Tobacco Mosaic Virus

Yellow Fever

Poliomyelitis Virus

Hepatitis B Virus

Bacteriophage

Bacteriophage Lysogeny

Rous Sarcoma Virus

Polyoma Virus

Reverse Transcriptase

Viral Oncogenes

Kuru

Prions

Parasites

Malaria

Cancer Parasite

DDT

Counterpoint: HIV / AIDS

Index