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Original Essays | November 5, 2009

John Buntin: IMG Notes from the (Bibliographic) Underground

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For more than 60 years, Los Angeles's origins, its underbelly, and (yes) its blondes have fueled the imagination of writers and directors from... Continue »
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    L.A. Noir: The Struggle for the Soul of America's Most Seductive City

    John Buntin

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Adenosine Receptors and Parkinson's Disease

by Hiroshi Kase

Adenosine Receptors and Parkinson's Disease Cover

Synopses & Reviews

Publisher Comments:

This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on "vitro" and "in vivo" systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease. <BR>Key Features<BR>* Discusses the discovery and development of a novel non-dopaminomimetic agent for Parkinson's disease<BR>* Provides the first definitive overview of adenosine antagonists and their role in the treatment of Parkinson's disease<BR>* Presents a new mechanism of action of adenosine A2A receptor antagonists in motor function<BR>Proposes a hypothesis of adenosine A2A receptor function in the striatum<BR>* Comprehensive overview of adenosine, its receptor subtypes, their antagonists/agonists from biochemistry, molecular biology, medicinal chemistry, physiology, pharmacology, and neurochemistry viewpoints

Book News Annotation:

Offers an overview of adenosine antagonists and Parkinson's disease. Delineates a novel mechanism and concept of adenosine receptor antagonists, explaining groundbreaking research in biochemistry, molecular biology, medicinal chemistry, electrophysiology, pharmacology, and neurochemistry. Discusses the development of a novel non-dopaminomimetic agent for Parkinson's disease, presents a new mechanism of action of adenosine receptor antagonists in motor function, and proposes a hypothesis of adenosine receptor function in the striatum. Kase is involved in pharmaceutical research and development at a Japanese company; Richardson teaches pharmacology at the University of Cambridge; Jenner is affiliated with the Neurodegenerative Diseases Research Center at King's College London.
Annotation c. Book News, Inc., Portland, OR (booknews.com)

Synopsis:

try to delineate a novel mechanism and concept of adenosine A2A receptor antagonists for the therapeutic approach to Parkinson's disease.

Synopsis:

and concept of adenosine A2A receptor antagonists for the therapeutic approach to Parkinson's disease.
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Table of Contents

lites in Movement Disorders.

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Product Details

ISBN:
9780124004054
Editor:
Kase, Hiroshi
Editor:
Richardson, Peter J.
Editor:
Richardson, Peter J.
Editor:
Jenner, Peter
Editor:
Kase, Hiroshi
Author:
Jenner, Richardson, Kase, Hiroshi, Peter J., Peter
Author:
Jenner, Richardson, Kase, Hiroshi, Peter, Peter
Editor:
Jenner, Peter
Publisher:
Academic Press
Location:
San Diego, CA
Subject:
Neurology
Subject:
Biochemistry
Subject:
Neuroscience
Subject:
Pharmacology
Subject:
Therapeutic use
Subject:
Parkinson Disease
Subject:
Parkinson's disease
Subject:
Adenosine
Subject:
Receptors, Purinergic P1
Subject:
Antagonists
Subject:
Neurology - General
Subject:
Adenosine -- Receptors.
Edition Description:
Includes bibliographical references and index.
Publication Date:
October 1999
Binding:
Hardcover
Language:
English
Illustrations:
Yes
Pages:
275
Dimensions:
9 x 6 in.
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