This volume presents results from the tenth anniversary meeting of the British Association for Psychopharmacology. It differs from previous BAP monographs in being a general review of the entire discipline, describing extensive recent progress, and identifying areas where work remains to be done. The papers focus on five major areas: depression and antidepressants, anxiolytics, cognitive disorders (particularly Alzheimer's disease), schizophrenia, and various forms of drug addiction. Topics addressed include the proliferation of new pharmaceutical agents, undesirable side effects, the potential hazards of current emphasis on the dopamine overactivity hypothesis, and the impact of CNS drugs. This will be an important resource for clinicians in neurology, psychiatry, and pharmacology; pharmacologists; and students and researchers in psychology, especially neuropsychology and behavioral pharmacology.

see 1908

' PART I: AFFECTIVE DISORDERS

1. How Effective are Antidepressants?

2. The Biology of Depressive Illness: 5-HT and Other Matters

3. Platelet Transport and Receptor Sites in Depressive Illness

4. Animal Models of Depression

5.Antidepressant Drugs of the Future

PART II: ANXIOLYTICS

6. Anxiolytics in Society

7. Where in the CNS do Benzodiazepines Act?

8. Pharmacokinetics and Pharmacodynamic Relationships with Benzodiazepines

9. Anxiety and its Generation by Pharmacological Means

10. Prospects in Treating Anxiety

PART III: PSYCHOPHARMACOLOGY AND COGNITION

11. Psychopharmacology of Cognition

12. Alzheimer\'s Disease and Parkinson\'s Disease

13. CNS Patterns of Neurochemical Abnormality in Cognitive Disorders

14. Neuropsychological Evaluation of Higher Cognitive Function in Animals and Man

15. The Study of Cholinomimetics in Alzheimer\'s Disease and Animal Models

PART IV: SCHIZOPHRENIA

16. Schizophrenia: Genetics and Environment

17. Structural Changes in the Brain in Schizophrenia

18. Mechanism of Action of Antipsychotic Drugs

19. Dopamine D2 Receptors and Schizophrenia

20. Integrated Viral Genes as the Cause of Schizophrenia

PART V: EUPHORIANTS AND STIMULANTS

21. Opioids

22. Alcohol

23. CNS Stimulants

24. Central Effects of Caffeine in Man

25. Aphrodisiacs

26. Nicotine Pharmacology and Smoking Dependence

27. How Amphetamine Works

'