In a multidimensional, intricately wrought narrative, Myla Goldberg leads us back to Boston in the early part of the twentieth century and into two completely captivating worlds. One is that of Lydia, an Irish American shopgirl with bigger aspirations than your average young woman from South Boston. She seems to be well on her way to the life she has dreamed of when she marries Henry Wickett, a shy medical student and the scion of a Boston Brahmin family. However, soon after their wedding, Henry abruptly quits medical school to create a mail-order patent medicine called Wickett's Remedy, and just as Lydia begins to adjust to her husband's new vocation, the infamous Spanish influenza epidemic of 1918 begins its deadly sweep across the world, irrevocably changing their lives.

In a world turned almost unrecognizable by swift and sudden tragedy, Lydia finds herself working as a nurse in an experimental ward dedicated to understanding the raging epidemic — through the use of human subjects.

Meanwhile, a parallel narrative explores the world of QD Soda, the illegitimate offspring of Wickett's Remedy, stolen away by Henry Wickett's one-time business partner Quentin Driscoll, who goes about transforming it into a soft drink empire.

Throughout the novel we hear from a chorus of other voices who offer a running commentary from the book's margins, playing off the ongoing narrative and cleverly illuminating the slippery interplay of perception and memory. Based on years of research and evoking actual events, Wickett's Remedy perfectly captures the texture of the times and brings a colorful cast of characters vividly to life — none more so than Lydia, a heroine as winning and appealing as Eliza, the beloved spelling champion of Bee Season.

With dazzling dexterity, Goldberg has fashioned a novel that beautifully combines the intimate and the epic. Wickett's Remedy announces her arrival as a major novelist.

"The author of the bestselling Bee Season returns with an accomplished but peculiarly tensionless historical novel that follows the shifting fortunes of a young Irish-American woman. Raised in tough turn-of-the-century South Boston, Lydia Kilkenny works as a shopgirl at a fancy downtown department store, where she meets shy, hypochondriacal medical student Henry Wickett. After a brief courtship, the two marry (Henry down, Lydia decidedly up) in 1914. Henry quits school to promote his eponymous remedy, whose putative healing powers have less to do with the tasty brew that Lydia concocts than with the personal letters that Henry pens to each buyer. After failing to pass the army physical as the U.S. enters WWI, Henry quickly, dramatically dies of influenza, and Lydia returns to Southie, where she watches friends, neighbors and her beloved brother die in the 1918 epidemic. A flu study that employs human subjects is being conducted on Boston Harbor's Gallups Island; lonely Lydia signs on as a nurse's assistant, and there finds a smidgen of hope and a chance at a happier future. A pastiche of other voices deepens her story: chapters close with snippets from contemporary newspapers, conversations among soldiers and documents revealing the surprising fate of Wickett's Remedy. And the dead offer margin commentary — by turns wistful, tender and corrective (and occasionally annoying). Yet as well-researched, polished and poignant as the book is, Goldberg never quite locks in her characters' mindsets, and sometimes seems adrift amid period detritus. While readers will admire Lydia, they may not feel they ever truly know her. Agent, Wendy Schmalz. (Sept.)" Publishers Weekly (Copyright Reed Business Information, Inc.)

"[A] rich historical re-creation whose energy and ingenuity evoke memories of E.L. Doctorow's classic Ragtime....A fine novel very much in the American vein, and a quantum leap forward for the gifted Goldberg." Kirkus Reviews

"Like Bee Season, this sorrowful, humorous, and tender novel utterly satisfies. Congratulations to Goldberg on another masterpiece; highly recommended." Library Journal

"Goldberg guides us through...wonderfully well-written chapters that would have made a strong short novel all on their own. Unfortunately, the book's power dissipates in its final movement." New York Times

"Heavy on period detail and literary style, but light on plot, Myla Goldberg's disappointing second novel is easy to set down." Rocky Mountain News

"In spite of its ornate structure, Wickett's Remedy is an appealingly straightforward tale about strength of spirit in times of crisis." Minneapolis Star Tribune

The triumphant follow-up to the bestselling Bee Season, Wickett's Remedy is a brilliant novel about the dream of progress — personal, scientific, commercial, and cultural — featuring a charming heroine whose desire for a better life comes up against the sweep of history.

Myla Goldberg is the author of the bestselling Bee Season, which was named a New York Times Notable Book in 2000 and made into a film, and, most recently, of Time's Magpie, a book of essays about Prague. Her short stories have appeared in Harper's, McSweeney's, and failbetter. She lives in Brooklyn, New York.