shopping cart
Save up to 30% on our Staff Picks
Call us: 800-878-7323 HELP
McAfee SECURE helps keep you safe from identity theft, credit card fraud, spyware, spam, viruses and online scams.
Original Essays | November 9, 2009

Jesse Bullington: IMG Abash'd the Devil Stood

0 comments By Jesse Bullington

I don't believe in evil. It's a word I use, certainly, because words are shortcuts and we all take the short way round from time to time, but that's... Continue »
  1. $10.49 Sale Trade Paper add to wish list

    The Sad Tale of the Brothers Grossbart

    Jesse Bullington

Basic Science for the Cardiologist #19: Adrenomedullin in Cardiovascular Disease

by Toshio Nishikimi

Basic Science for the Cardiologist #19: Adrenomedullin in Cardiovascular Disease Cover

Synopses & Reviews

Publisher Comments:

Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has role in the pathogenesis of arteriosclerosis. Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.
back to top

Table of Contents

Introduction.- Biochemistry of Adrenomedullin.- Adrenomedullin Receptor and Signal Transduction.- Adrenomedullin Gene.- Adrenomedullin Expression and Secretion.- Biological Action of Adrenomedullin.- Circulating Adrenomedullin.- Role of Adrenomedullin in Cardiovascular Disease.- Adrenomedullin as an Adipokine.- Adrenomedullin Knockout Mouse and Transgenic Mouse.- Pleiotropic Effect of Adrenomedullin, Lessons from Pure Adrenomedullin Knockout Mouse.- Therapeutic Application of Adrenomedullin.- Therapeutic Potentials of Adrenomedullin for Heart Failure and Pulmonary Hypertension.- Index.

back to top
back to top

Product Details

ISBN:
9780387254043
Editor:
Nishikimi, Toshio
Publisher:
Springer Us
Other:
Nishikimi, Toshio
Editor:
Nishikimi, Toshio
Subject:
Diseases
Subject:
Physiology
Subject:
Cardiology
Subject:
Cardiovascular diseases -- Drug therapy.
Subject:
Peptide hormones.
Series:
Basic Science for the Cardiologist
Series Volume:
19
Publication Date:
April 2005
Binding:
Hardcover
Language:
English
Illustrations:
Y
Pages:
219
Dimensions:
9.58x6.36x.71 in. 1.15 lbs.
back to top

Related Aisles

  • back to top

Powell's City of Books is an independent bookstore in Portland, Oregon, that fills a whole city block with more than a million new, used, and out of print books. Shop those shelves — plus literally millions more books, DVDs, and eBooks — here at Powells.com.