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Book News, Guests | December 14, 2009

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Gamma-Hydroxybutyrate: Molecular, Functional and Clinical Aspects

by Godfrey Tunnicliff

Gamma-Hydroxybutyrate: Molecular, Functional and Clinical Aspects Cover

Synopses & Reviews

Publisher Comments:

Gamma-hydroxybutyrate (GHB) has come a long way since early experiments in animals where it was found to induce a sleep-like state and from its use in general anaesthesia in human subjects. It has been found to be a naturally-occurring compound in the brain, a metabolite of GABA, the emerging ubiquitous inhibitory neurotransmitter. This has opened up a completely new line of research in an effort to establish a function for GHB. Gamma-Hydroxybutyrate: Pharmacological and Functional Aspects has brought together the combined expertise of many of the leading authorities on the biochemistry, physiology and pharmacology of GHB in the central nervous system. Each chapter is an in-depth review of the field and the book itself will appeal to all neurobiologists interested in neurotransmitter mechanisms, as well as to clinicians and other health-care workers interested in this fascinating chemical.

Book News Annotation:

A naturally occurring metabolite of the inhibitory neurotransmitter GABA, gamma-hydroxybutyrate (GHB) is being investigated for its efficacy in treating sleep disorders, fibromyalgia, and drug addiction. Its euphoric and sleep-inducing effects have unfortunately also led to its abuse as a "date rape drug." Aimed at neurobiologists and clinicians, this volume contains 14 contributions from international researchers on the biochemistry, physiology, and pharmacology of GHB in the central nervous system. Tunnicliff teaches at Indiana U. School of Medicine and Cash is with CNRS in Strasbourg, France. Annotation (c)2003 Book News, Inc., Portland, OR (booknews.com)

Synopsis:

Gamma-hydroxybutyrate (GHB) has come a long way since early experiments in animals where it was found to induce a sleep-like state, and from its use in general anesthesia in human subjects. Soon it was found to be a naturally-occuring compound in the brain. This title concerns this compound.

Product Details

ISBN:
9780415284998
Subtitle:
Pharmacological and Functional Aspects
Author:
Tunnicliff, Godfrey
Author:
Tunnicliff, Tunnicliff
Author:
Cash, Christopher D.
Publisher:
CRC Press
Location:
London
Subject:
Pain Medicine
Subject:
Brain
Subject:
Diseases - Brain
Subject:
Neurochemistry
Subject:
GABA.
Subject:
Life Sciences - Biochemistry
Subject:
Neurology - General
Subject:
Sodium Oxybate
Edition Description:
Includes bibliographical references and index.
Series Volume:
107-138
Publication Date:
August 2002
Binding:
Hardcover
Language:
English
Illustrations:
Yes
Pages:
268
Dimensions:
9.38x7.52x.70 in. 1.51 lbs.

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