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Cancer Metastasis: In Vitro and in Vivo Experimental Approaches

by D. Rusciano

Synopses & Reviews

Publisher Comments:

The book describes most of the methods that are currently used in metastasis research. Both in vivo and in vitro protocols are illustrated, so that the metastatic process can be either analysed as a whole, or single events addressed separately. Each method is described in the frame of the metastatic process, therefore its significance and its limitations in the context of metastasis are always taken into account. Whenever possible, several alternative procedures are reported per each experimental issue, so that the researcher can choose the one that better suits her/his needs and possibilities.

During the past 30 years a big effort has been made to elucidate the molecular mechanisms of cancer metastatis, the leading cause of death for cancer patients. A considerable number of assays have been set up, that can be used to address specific questions concerning the single metastatic steps, or can be applied to develop and test drugs specifically interfering with selected events during the metastatic spread. This book contains an exhaustive description of most of the methods and their rationale, that are currently used in metastatic research, both to analyse metastasis in its entirety (in vivo models), or to dissect the single steps of the metastatic process (in vitro assays).

Product Details

ISBN:
9780444823724
Subtitle:
Experimental Approaches
Author:
Rusciano, D.
Author:
Burger, M. M.
Author:
Welch, Burger, Rusciano, D., M.M., D.R.
Author:
Welch, D. R.
Publisher:
Elsevier Science & Technology
Subject:
Biochemistry
Subject:
Research
Subject:
Genetics
Subject:
Oncology
Subject:
Pharmacology
Subject:
Neoplasm Metastasis -- genetics.
Subject:
Neoplasm Metastasis -- physiopathology.
Series:
Laboratory Techniques in Biochemistry and Molecular Biology
Series Volume:
29
Publication Date:
December 2000
Binding:
Hardcover
Language:
English
Illustrations:
Y
Pages:
372
Dimensions:
5.31 x 7.87 in

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