A Practical Guide to Supramolecular Chemistryis an introductory manual of practical experiments for chemists with little or no prior experience of supramolecular chemistry. Syntheses are clearly presented to facilitate the preparation of acyclic and macrocyclic compounds frequently encountered in supramolecular chemistry using straightforward experimental procedures.

Many of the compounds can be used to illustrate classic supramolecular phenomena, for which clear directions are given, or may be developed further as part of the reader’s own research. The book also describes techniques commonly used in the analysis of supramolecular behaviour, including computational methods, with many detailed examples.

An invaluable reference for students and researchers in the field embarking on supramolecular chemistry projects and looking for a ‘tried and tested’ route into the chemistry of key compounds.

An introductory guide to practical syntheses focusing on supramolecular chemistry.

Fully referenced introductions explain the historical and contemporary importance of each compound

Supplementary website including 3D molecular structures, FAQ’s about syntheses and suggestions for further experiments

Designed for students and researchers with little or no prior experience in the field, this text introduces the basics of supramolecular chemistry through a series of easily reproducible laboratory procedures. Many of the compounds thus prepared may be used to illustrate particular supramolecular phenomena (such as clathrate formation) or may be developed further as part of the researcher's own work. Some computational methods used in the analysis of supramolecular behavior are also described. Cragg teaches biomolecular sciences at the U. of Brighton, UK.
Annotation ©2006 Book News, Inc., Portland, OR (booknews.com)

Designed for students and researchers with little or no prior experience in the field, this text introduces the basics of supramolecular chemistry through a series of easily reproducible laboratory procedures. Many of the compounds thus prepared may be used to illustrate particular supramolecular phenomena (such as clathrate formation) or may be developed further as part of the researcher's own work. Some computational methods used in the analysis of supramolecular behavior are also described. Cragg teaches biomolecular sciences at the U. of Brighton, UK. Annotation ©2006 Book News, Inc., Portland, OR (booknews.com)

"…an introduction to supramolecular chemistry…recommended." (CHOICE, May 2006)

Supplementary website including 3D molecular structures, FAQ's about syntheses and suggestions for further experiments

Dr Peter J. Cragg, School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK

Introduction.

1 Linear components for supramolecular networks.

1.1 Flexible components.

1.2 Rigid components from Schiff bases.

1.3 Flexible tripods.

1.4 Simple anion hosts.

1.5 Rigid platforms.

2 Cyclic synthons.

2.1 Planar macrocycles from nature.

2.2 Artificial planar macrocycles – phthalocyanines and other cyclic systems.

2.3 Serendipitous macrocycles.

2.4 Adding functionality to the crowns.

2.5 Azacrowns with sidearms.

2.6 Water-soluble macrocycles.

2.7 Catenanes and rotaxanes.

3 Molecular baskets, chalices and cages.

3.1 One for beginners.

3.2 Calixarenes – essential supramolecular synthons.

3.3 Adding lower rim functionality to the calixarenes.

3.4 Adding upper rim functionality to the calixarenes.

3.5 Oxacalix[3]arenes.

3.6 Oxacalixarene derivatives.

3.7 Azacalix[3]arenes.

3.8 Calixarene variations.

3.9 Molecular cages for cations and anions.

4 Supramolecular assembly.

4.1 Detection, measurement, prediction and visualization.

4.2 X-ray crystallography.

4.3 Spectroscopic and spectrometric techniques.

4.4 Binding constant determination.

4.5 Solid state vs. solution behaviour.

4.6 Supramolecular chemistry in silico: molecular modelling and associated techniques.

4.7 Computational approaches.

4.8 A protocol for supramolecular computational chemistry.

4.9 Examples of in silico supramolecular chemistry.

5 Supramolecular phenomena.

5.1 Clathrates.

5.2 Stabilization of cation–anion pairs by crown ethers: liquid clathrates.

5.3 Receptors for the ammonium ion.

5.4 Purification of fullerenes.

5.5 Making molecular boxes and capsules.

5.6 Self-complementary species and self-replication.

Appendix 1 Integrated undergraduate projects.

Appendix 2 Reagents and solvents.

Index.