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On Order $72.50
New Trade Paper
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Principles of Cell Proliferationby John K. Heath
Synopses & ReviewsPublisher Comments:Controlled expansion of cell populations is a fundamental feature of living organisms, being a finely-tuned balance between cell proliferation and cell death. This book aims to explain the molecular mechanisms that lie behind the multiplication and survival of eukaryotic cells. This encompasses both the normal regulation of cell populations in development or physiological adaptation and pathological mechanisms of cell cycle control in cancer. Principles of Cell Proliferationprogressively introduces the function of growth factors, receptors, signal transduction pathways, gene expression, and the conserved mechanisms of the cell cycle engine. This provides a context for understanding the mechanistic consequences of the genetic alterations in oncogenes and tumour suppresser genes which underlie tumour formation. The book should satisfy advanced level courses in Cell Proliferation, Cell Cycle Control and Cancer Biology for biologists, biochemists and medical students. Book News Annotation:Heath (biosciences, University of Birmingham) aims to explain the
molecular mechanisms that lie behind the multiplication and survival
of eukaryotic cells. This encompasses both the normal regulation of
cell populations in development or physiological adaptation and
pathological mechanisms of cell cycle control in cancer. This book
progressively introduces the function of growth factors, receptors,
signal transduction pathways, gene expression, and the conserved
mechanism of the cell cycle engine. This provides a context for
understanding the mechanistic consequences of the genetic alterations
in oncogenes and tumor suppressor genes which underlie tumor
formation.
Annotation c. Book News, Inc., Portland, OR (booknews.com) Synopsis:This book aims to explain the molecular mechanisms, which lie behind the decision of an individual cell to multiply. This includes not only the normal regulation of cell proliferation in response to external stimuli but also malignant cell proliferation in cancerous cells. The book presents the cell cycle in a linear fashion, progressively introducing the role of growth factors, their receptors and linking these to signal transduction pathways. The effect of oncogenes, counteracting tumor suppressor genes and apoptosis (or programmed cell death) is all introduced within this framework. Coming at a time when the underlying molecular mechanisms of cancer are beginning to be unraveled, the book should satisfy advanced level courses in Cell Proliferation, Cell Cycle and Cancer Biology for biochemists and medical students. Description:Includes bibliographical references (p. 131-133) and index. Table of ContentsPreface. 1. Biology of the Cell Cycle. 2. Growth Factors. 3. Receptors. 4. Intracellular Signals. 5. Gene Expression. 6. The Cell Cycle Engine. 7. Oncogenes. 8. Tumour Suppressor Genes. 9. Cell Survival. Index What Our Readers Are SayingBe the first to add a comment for a chance to win!Product Details
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