In Evidence-based Neurology: Management of Neurological Disorders, a carefully selected group of clinically experienced collaborators use the best available evidence to answer more than 100 clinical questions about the treatment and management of neurological disorders.

Divided into three sections and 24 chapters, Evidence-based Neurology: Management of Neurological Disorders:

• fills the gap between guidelines and primary studies as well as between primary and secondary scientific medical literature

• summarizes the most recent and important findings on treatments for neurological patients

• measures the benefit and, when applicable, the risk of harm inherent in specific neurological interventions.

Each chapter starts with a brief definition of the clinical condition, together with its incidence and natural history. A clear formulation of a real-world scenario or question usually follows, structured using the standard three elements of patient, intervention, and outcome. The results are as quantitative as possible.

This unique, evidence-based text, edited by members of the Cochrane Neurological Network will be an essential resource for all general neurologists, from the novice to the most experienced, in their everyday clinical practice.

A team of international experts headed by Candelise (Cochrane Neurological Network, U. of Milan, Italy) addresses some 100 clinical questions about the treatment and management of neurological disorders ranging from migraines to muscle disorders. After explaining what defines evidence-based medicine in the context of the reality of practicing in the absence of randomized controlled trials (advice: "do not succumb to EBMitis"), contributors present information on neurological symptoms/ problems common to several disorders and major diseases. The 20 chapters typically include background information, a critical review of the evidence for answerable clinical questions, treatments/rehabilitation services, summary tables, and references. Some include clinical scenarios and health research and policy implications. Distributed in the US by Blackwell Publishers. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)

“Chapters are well-written and balanced, carefully considering … the strengths and weaknesses of EBM … text will be useful for teaching medical students, residents … practicing neurologists and other clinicians.” Journal of the American Medical Association<!--end-->

“This book is a great help when patients confront me with information and I have to provide data on benefit or risk within 60 seconds.”

Lancet Neurology

“The writing style is simple and clear. The editors have produced a book that should be accessible to students and practitioners at all levels.”

Doody’s Review Service

In Evidence-based Neurology: Management of Neurological Disordersa carefully selected group of clinically experienced collaborators use the best available evidence to answer more than 100 clinical questions about the treatment and management of neurological disorders.

Divided into three sections and 24 chapters, this book

• fills the gap between guidelines and primary studies as well as between primary and secondary scientific medical literature

• summarizes the most recent and important findings on treatments for neurological patients

• measures the benefit and, when applicable, the risk of harm inherent in specific neurological interventions.

This unique, evidence-based text, edited by members of the Cochrane Neurological Network will be an essential resource for all general neurologists, from the novice to the most experienced, in their everyday clinical practice.

Livia Candelise, Cochrane Neurological Network, Dipartimento di Scienze Neurologiche, Ospedale Maggiore Policlinico, Universita’ degli Studi di Milano, Milan, Italy

Richard Hughes, Department of Clinical Neurosciences, King’s College London School of Medicine at Guy’s, King’s College and St Thomas’ Hospitals, London, UK

Alessandro Liberati. Department of Hematology and Oncology, University of Modena and Reggio Emilia, Azienda Ospedaliera Policlinico, Ferrara, Italy

Bernard Uitdehaag, Department of Neurology and Department of Clinical Epidemiology and Biostatistics, VU Medical Centre, Amsterdam, The Netherlands

Charles Warlow, Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK

Part 1 Introduction.

1 Evidence-based medicine: its contributions in the way we search, appraise and apply scientific information to patient care.

Alessandro Liberati, Lorenzo P. Moja, Ivan Moschetti.

2 What to do when there is no evidence.

Charles Warlow.

3 Outcome and adverse effect measures in neurology.

Jorge G. Burneo, Samuel Wiebe.

4 Systematic reviews of diagnostic research.

Bernard M.J. Uitdehaag, Peter M. Rothwell.

Part 2 Neurological symptoms/problems.

5 Acute migraine attacks.

Anne MacGregor.

6 Back and neck pain.

Harry McNaughton.

7 Neuropathic pain.

Giorgio Cruccu, Nadine Attal, Rod Taylor.

8 Vertigo and dizziness: treatment of benign paroxysmal positional vertigo, vestibular neuritis and Menière’s disease.

Michael Strupp, Thomas Brandt, Christian Daniel Cnyrim.

9 Sleep disorders.

Michel Billiard.

10 Cognitive rehabilitation of non-progressive neuropsychological disorders.

Stefano F. Cappa, Thomas Benke, Stephanie Clarke, Bruno Rossi, Brigitte Stemmer, Caroline M. van Heugten.

11 Management and pharmaceutical treatment of central and spinal spasticity.

David T. Shakespeare.

12 Background to neurorehabilitation.

Kathryn McPherson, Paula Kersten, Lynne Turner-Stokes.

Part 3 Neurological diseases.

13 Acute stroke management and prevention of recurrences.

Gord Gubitz.

14 Aneurysmal subarachnoid haemorrhage.

Jan van Gijn, Gabriel J.E. Rinkel.

15 Acute traumatic brain injury.

Miguel F. Arango, Walter Videtta, Corina Puppo.

16 Corticosteroids in central nervous system infections.

Anu Jacob, Tom Solomon, Paul Garner.

17 Brain tumours.

Michael G. Hart, Robin Grant.

18 Epilepsy.

Sridharan Ramaratnam, Anthony Marson.

19 Dementia treatment: let the evidence lead us.

Bart M. Demaerschalk, Bryan K. Woodruff, Richard J. Caselli.

20 Parkinson’s disease.

Miguel Coelho, Joaquim Ferreira, Cristina Sampaio.

21 Multiple sclerosis: critical review of the evidence for each question.

Graziella Filippini, George Ebers.

22 Motor neurone disorders.

Douglas Mitchell.

23 Peripheral nerve disorders.

Richard Hughes, Eva L. Feldman, Jeremy D.P. Bland.

24 Muscle disorders.

Fiona Norwood, Michael R. Rose.

Index