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Check for Availabilityout of stock. Click on the button below to search for this title in other formats.  Cytotoxic Cells: Basic Mechanisms and Medical Applications
Synopses & ReviewsPublisher Comments:This volume synthesizes recent groundbreaking advances in our knowledge of the molecular mechanisms, biological roles, and medical applications of cytotoxic lymphocytes. Leading investigators examine current concepts on the recognition of antigen by T-cell receptors; the molecules mediating target recognition by natural killer cells; the intracellular signalling cascades triggered by these molecules; and the effector molecules that damage target cells. The contributors present new insights into the roles of cytotoxic lymphocytes in vivo in immune regulation, autoimmunity, antiviral resistance, and tumor surveillance. Several chapters explore potential medical applications of cytotoxic lymphocytes, including vaccines, tumor therapy, and treatment of HIV infection. Book News Annotation:Serving as a single source overview and reference in the field, this
volume contains 31 contributions, arranged in the following
sections: historical overview; target cell recognition; effector cell
signaling pathways; cytotoxic effector molecules; cytotoxic
lymphocytes in vivo; CTL generation and memory; and medical
applications of cytotoxic lymphocytes. Researchers from the US,
Europe, and Australia present sometimes conflicting research in a
number of areas, with the last section chronicling exciting new
developments in the creation of potent cytotoxic effector cells in
vitro, as well as the extension of these ideas as a possible means
of treating HIV infection.
Annotation c. Book News, Inc., Portland, OR (booknews.com) What Our Readers Are SayingBe the first to add a comment for a chance to win!Product Details
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