This comprehensive reference emphasizes the dynamic events that occur in the maintenance and repair of blood vessels in health and abnormalities that may result from dysregulation of inflammatory and immune responses in disease. The editors have assembled authors and topics that bring new concepts about cell and molecular biology to the clinician to provide a better understanding of pathogenesis, the diagnostic process, and treatment. Recent insights into pathogenesis have dramatically influenced development of new therapies that target disease pathways. Inflammatory Diseases of Blood Vessels discusses 7organ selectivity in varying forms of vascular disease 7mechanisms of arterial tissue injury 7functions of the extracellular matrix 7cytokine expression in vasculitic disorders 7diagnostic approaches to 10 and 20 vasculitis 7conventional therapies 7new targets for immunotherapy 7and more! With contributions by 90 leading worldwide authorities in the field and providing over 4700 valuable references, drawings, photographs, micrographs, and tables, Inflammatory Diseases of Blood Vessels is an authoritative and essential resource for rheumatologists, pathologists, cardiologists, immunologists, allergists, nephrologists, pulmonologists, vascular and cardiothoracic surgeons, and trainees in these disciplines.

A comprehensive overview of the science and clinical consequences of vascular inflammation in health and disease. Fifty-two articles by 90 contributors from around the globe address such topics as neutrophils in vasculitis, oxygen metabolites and vascular damage, T-cells in vascular disease. Other articles focus on primary and secondary vasculitides such as Kawasaki Disease, Takayasu's Arteritis, relapsing polychondritis, and dyslipidemia in rheumatic disorders. Articles feature introductions and the contributor's association is also provided. Ample visual information is provided in the form of drawings and color and b&w plates.
Annotation c. Book News, Inc., Portland, OR (booknews.com)