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Mass Spectrometry in Drug Discovery Discovery, Bioanalysis, and Clinical Diagnostics

by Rossi T. Rossi

Mass Spectrometry in Drug Discovery Discovery, Bioanalysis, and Clinical Diagnostics Cover

Synopses & Reviews

Publisher Comments:

Mass Spectrometry in Drug Discovery summarizes the theory, instrumentation, techniques, and application of mass spectrometry and atmospheric pressure ionization to screening, evaluating, and improving the performance and quality of drug candidates. It provides time- and cost-efficient approaches for the generation and analysis of effective pharmaceuticals, covers advances in combinatorial chemistry, molecular biology, bioanalysis automation, and computing, and demonstrates the use of mass spectrometry in the assessment of disease states, drug targets, and potential drug agents.

Book News Annotation:

Thirteen chapters summarize the theory, instrumentation, and application of mass spectrometry and atmospheric pressure ionization to the evaluation of drug candidates. It describes current techniques in pharmaceutics and pharmacokinetics for increased quantities of new pharmacological compounds. Chapters discuss ion chemistry and fragmentation, the LC/MS experiment, drug hydrophobicity and transport, drug metabolism, cassette dosing, microdialysis, and related subjects. Contributors include chemists at universities and researchers for drug companies.
Annotation c. Book News, Inc., Portland, OR (booknews.com)

Product Details

ISBN:
9780824706074
Editor:
Rossi, David T.
Editor:
Sinz, Michael W.
Editor:
Rossi, David T.
Editor:
Sinz, Michael W.
Author:
Rossi, Rossi T.
Publisher:
CRC Press
Location:
New York
Subject:
Drugs
Subject:
Chemistry - General
Subject:
Pharmacy
Subject:
Mass spectrometry
Subject:
Drugs -- Analysis.
Edition Description:
Includes bibliographical references and index.
Series Volume:
107-125
Publication Date:
November 2001
Binding:
Hardcover
Language:
English
Illustrations:
Yes
Pages:
432
Dimensions:
9.42x6.38x.98 in. 1.61 lbs.

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