With contributions from recognized authorities in industry, academia, and government, this reference presents the state-of-the-art in the testing, formulation, and clinical evaluation of intraoral drug delivery products-summarizing intraoral dosage forms in various stages of research, as well as products currently on the market.

Fourteen papers, presented by Ghosh (Office of Clinical Pharmacology and Biopharmaceutics, Federal Department of Agriculture) and Pfister (Senior Director Preclinical Affairs, NexMed Inc.), review the state of the science and innovative technologies for the pharmaceutical development of solid-state dosage for oral transmucosal drug delivery and oral mucosal drug delivery systems. After an overview of the fundamentals, contributions address such topics as preclinical assessment of oral mucosal systems; modulation of oral transmucosal permeability; oral transmucosal delivery of protein and peptide therapeutics; sublingual transmucosal delivery of organic nitrates for the treatment of angina pectoris; oral transmucosal delivery of melatonin; oral transmucosal powder injection; drug delivery systems for the treatment of periodontal and dental diseases; oral transmucosal systems for local anesthetics; quick-dispersing oral drug delivery systems; and scientific and regulatory considerations of quick-dissolving oral dosage forms. Appendixes offer reference guides to companies developing intraoral drug delivery technologies and products, and books and market research reports on such companies.
Annotation ©2005 Book News, Inc., Portland, OR (booknews.com)

Fourteen papers, presented by Ghosh (Office of Clinical Pharmacology and Biopharmaceutics, Federal Department of Agriculture) and Pfister (Senior Director Preclinical Affairs, NexMed Inc.), review the state of the science and innovative technologies for the pharmaceutical development of solid-state dosage for oral transmucosal drug delivery and oral mucosal drug delivery systems. After an overview of the fundamentals, contributions address such topics as preclinical assessment of oral mucosal systems; modulation of oral transmucosal permeability; oral transmucosal delivery of protein and peptide therapeutics; sublingual transmucosal delivery of organic nitrates for the treatment of angina pectoris; oral transmucosal delivery of melatonin; oral transmucosal powder injection; drug delivery systems for the treatment of periodontal and dental diseases; oral transmucosal systems for local anesthetics; quick-dispersing oral drug delivery systems; and scientific and regulatory considerations of quick-dissolving oral dosage forms. Appendixes offer reference guides to companies developing intraoral drug delivery technologies and products, and books and market research reports on such companies. Annotation ©2005 Book News, Inc., Portland, OR (booknews.com)

With contributions from recognized authorities in industry, academia, and government, Drug Delivery to the Oral Cavity: Molecules to Market provides information unavailable elsewhere in the literature on recently commercialized and emerging intraoral drug delivery products. It presents the state-of-the-art in the testing, formulation, and clinical evaluation of intraoral drug delivery products and summarizes intraoral dosage forms in various stages of research, as well as products currently on the market. Emphasizing the impact of intraoral drug delivery and its advantages over conventional oral dosage forms, this handbook covers the latest research concerning drug delivery to the oral cavity.