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DNA Methylation: Approaches, Methods, and Applications

by Manel Esteller

DNA Methylation: Approaches, Methods, and Applications Cover

Synopses & Reviews

Publisher Comments:

DNA Methylation: Approaches, Methods and Applications describes the relation DNA methylation has to gene silencing in disease, and explores its promising role in treating cancer. Written by leaders in the field, this exceptional compilation of articles outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA. It includes concepts, experimental models, and clinical uses of demethylating agents. The book provides a balance between articles clarifying methodological details and more general review chapters that offer broad biological perspectives on DNA methylation. This is an invaluable handbook for researchers and clinicians interested in genetics and molecular biology, particularly epigenetic therapies and gene silencing.

Book News Annotation:

Esteller (Spanish National Cancer Center, Spain) provides an understanding of theory, technologies, and applications of DNA methylation. Contributors offer research, clinical, and industry perspectives on the regulatory roles of DNA methylation, the relation that this biological mechanism has to gene silencing in disease, and its promising role in treating cancer. While some chapters offer a broad overview of biological perspectives on DNA methylation, others clarify methodological details. The book is for researchers and clinicians in genetics and molecular biology, particularly epigenetic therapies and gene silencing.
Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)

Product Details

ISBN:
9780849320507
Subtitle:
Approaches, Methods, and Applications
Author:
Esteller, Manel
Publisher:
CRC Press
Subject:
Genetics
Subject:
Histology
Subject:
Oncology
Subject:
Dna
Subject:
Methylation
Subject:
DNA -- Methylation.
Publication Date:
September 2004
Binding:
Paperback
Language:
English
Illustrations:
Y
Pages:
240
Dimensions:
9.50x6.38x.73 in. 1.08 lbs.

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