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Methods in Signal Transduction #6: G Protein-Coupled Receptors

by Tatsuya Haga

Methods in Signal Transduction #6: G Protein-Coupled Receptors Cover

Synopses & Reviews

Publisher Comments:

With contributions from international experts in the fields of pharmacology, neuroscience, and biochemistry, this text provides an in-depth exploration of GPCRs. Coverage includes the screening of ligands for GPCRs, physiological and molecular characterizations of GPCRs, and structures of GPCRs and their ligands. The book explores current research issues in the post-genome era, particularly the identification of endogenous ligands that may lead to finding new hormones or neurotransmitters. It also discusses the determination of the tertiary structure of GPCRs, useful for understanding GPCR interactions and for the theoretical modeling of drugs.

Book News Annotation:

In an extension rather than update of the 1999 volume in the series G Protein-Coupled Receptors, mostly Japanese scientists describe techniques used to investigate and manipulate the receptors that either were not treated in the earlier volume or have been developed since it appeared. They cover the screening of ligands for the receptors, receptor functions and regulation, and the tertiary structure of the receptors and their ligands. Among specific topics are the ligand screening of olfactory receptors, the analysis of the regulation of muscarinic acetylcholine receptors, and modeling G protein-coupled receptors for drug design.
Annotation ©2005 Book News, Inc., Portland, OR (booknews.com)

Book News Annotation:

In an extension rather than update of the 1999 volume in the series G Protein-Coupled Receptors, mostly Japanese scientists describe techniques used to investigate and manipulate the receptors that either were not treated in the earlier volume or have been developed since it appeared. They cover the screening of ligands for the receptors, receptor functions and regulation, and the tertiary structure of the receptors and their ligands. Among specific topics are the ligand screening of olfactory receptors, the analysis of the regulation of muscarinic acetylcholine receptors, and modeling G protein-coupled receptors for drug design. Annotation ©2005 Book News, Inc., Portland, OR (booknews.com)

Product Details

ISBN:
9780849327711
Subtitle:
Structure, Function, and Ligand Screening
Author:
Haga, Tatsuya
Author:
Takeda, Shigeki
Author:
Haga, Haga
Publisher:
CRC Press
Subject:
Biochemistry
Subject:
Neuroscience
Subject:
G proteins
Subject:
Receptors
Subject:
Life Sciences - Biochemistry
Subject:
G proteins -- Receptors.
Edition Number:
6
Series:
Methods in Signal Transduction
Series Volume:
6
Publication Date:
August 2005
Binding:
Hardcover
Language:
English
Illustrations:
Y
Pages:
336
Dimensions:
9.62x6.12x.90 in. 1.39 lbs.

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