Congenital Diseases of the Heart: Clinical-Physiological Considerations, Fully Revised and Updated Second Edition represents the accumulated experiences of the author. Dr. Abraham M. Rudolph is recognized internationally as a leading contributor in the field of Pediatric Cardiology. Since the publication of the book's first edition in 1974, remarkable achievements in diagnostic and therapeutic techniques have been attained, making possible and necessary this thorough update of the work. A uniquely important contribution of this new edition is the discussion of the hemodynamic and clinical features and their impact at various stages of development-from fetus to neonate to infant to child and adolescent. Due to the advent of prenatal ultrasound and Doppler flow studies, concepts of the influence of congenital cardiac lesions that were once based largely on conjecture can now be measured, compared, and quantified. The book discusses congenital cardiac disorders from the perspective of the abnormal hemodynamics of the circulation, reviewing current concepts as well as controversial issues (such as the advisability of procedures for alleviating cardiac lesions in utero). The physiology of the fetal normal circulation is presented and the effects of congenital cardiac lesions are discussed with particular reference to the interactions between the lesions and fetal cardiovascular development. A list of carefully selected references offers further guidance to relevant literature. Pediatric cardiologists, neonatologists, and pediatric intensive care physicians, as well as clinicians treating adult patients with congenital heart diseases, will find this updated classic to be useful, informative, and enlightening.

Discusses congenital cardiac disorders from the perspective of the abnormal hemodynamics of circulation, reviewing current concepts as well as controversial issues such as the advisability of procedures for alleviating cardiac lesions in utero. The physiology of normal fetal circulation is presented and the effects of congenital cardiac lesions are discussed with particular reference for the interactions between the lesions and fetal cardiovascular development. Useful for pediatric cardiologists, neonatologists, and pediatric intensive care physicians. This second edition reflects advances in the field since the publication of the first edition in 1974. Rudolph is affiliated with the Cardiovascular Research Institute at the University of California-San Francisco.
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Includes bibliographical references (p. 763-790) and index.

General Considerations.

Chapter 1. Fetal Circulation and Postnatal Adapation.

Chapter 2. Functional Assessment.

Chapter 3. Oxygen Uptake and Delivery.

Chapter 4. Prenatal and Postnatal Pulmonary Circulation.

Lesions Associated with Left to Right Shunts.

Chapter 5. The Ductus Arteriosus and Persistent Patency of the Ductus Arteriosus.

Chapter 6. Ventricular Septal Defect.

Chapter 7. Atrial Septal Defect: Partial Anomalous Drainage of Pulmonary Veins.

Chapter 8. Atrioventricular Septal Defect.

Obstructive Lesions.

Chapter 9. Aortic Stenosis and Hypoplastic Left Ventricle.

Chapter 10. Aortic Arch Obstruction.

Chapter 11. Aortic Atresia, Mitral Atresia.

Chapter 12. Total Anomalous Pulmonary Venous Connection.

Chapter 13. Pulmonary Stenosis and Atresia with Ventricular Septal Defect (Tetralogy of Fallot).

Chapter 14. Pulmonary Stenosis and Atresia with Intact Ventricular Septum.

Chapter 15. Tricuspid Atresia and Hypoplastic Right Ventricle.

Chapter 16. Ebstein Malformation of the Tricuspid Valve.

Aorto-Pulmonary Anomalies.

Chapter 17 Transposition of the Great Arteries (Aorto-Pulmonary Transposition).

Chapter 18 Truncus Arteriosus Communis.

Selected References.

Index