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Principles of Molecular Regulation

by P. Michael Conn

Principles of Molecular Regulation Cover

Synopses & Reviews

Publisher Comments:

Principles of Molecular Regulation comprehensively describes the processes by which the brain acts as an endocrine organ to control hormonal functions, maintain homeostasis, and regulate behavior. The book describes basic neuroendocrine processes and presents them in a manner relative to clinical settings, thus providing an interface between basic and clinical observations. The authors are well recognized scientists and physicians selected for their contributions and facility of expression. This volume will be used by basic scientists and graduate students as well as clinicians, residents, interns and medical students. Physicians wishing to understand physiological principles will also find this book useful.

Book News Annotation:

Conn (Oregon Health Sciences U. and Oregon Regional Primate Research Center) and Means (pharmacology, Duke U.) have gathered 27 papers that survey the state of membrane receptor initiated cell signaling and nuclear receptor-initiated gene regulation. The material covers and integrates work from the fields of molecular biology, cell biology, and endocrinology. The papers are organized into sections discussing signaling mechanisms initiated by cell surface receptors; signaling mechanisms mediated by ion channels, calcium, and lipids; cyclic AMP, protein kinases, and protein phosphates; signaling mechanisms initiated by nuclear receptors; molecular regulation of cell proliferation and death; and rational drug discovery.
Annotation c. Book News, Inc., Portland, OR (booknews.com)

Synopsis:

P. Michael Conn and Anthony Means have successfully assembled a panel of leading investigators to provide an integrated review of the key areas-membrane receptor-initiated cell signaling and nuclear-receptor initiated gene regulation. Chosen for the excellence of their research, these distinguished authors illuminate the molecular machinery underlying the regulatory processes of cells. In addition to their comprehensive review of the signaling mechanisms involving cell surface receptors, nuclear receptors, and ion channels, they detail the roles of calcium, lipids, cyclic AMP, protein kinases, and protein phosphatases. Capturing the excitement now present at this vibrant union of molecular biology, cell biology, and endocrinology, Principles of Molecular Regulation constitutes a major new resource for understanding the many and complex elements of biological regulation. Its up-to-date critical synthesis is certain to prove of high value to all basic and clinical investigators working with these processes today.

Product Details

ISBN:
9780896036307
Editor:
Means, Anthony R.
Foreword:
O'Malley, Bert W.
Foreword:
O'Malley, Bert W.
Editor:
Conn, P. Michael
Author:
Conn, P. Michael
Author:
Means, Anthony R.
Publisher:
Humana Press
Location:
Totowa, N.J.
Subject:
Neurology
Subject:
Molecular biology
Subject:
Endocrinology & Metabolism
Subject:
Molecular endocrinology
Subject:
Cellular signal transduction
Subject:
Gene expression regulation.
Subject:
Signal Transduction.
Subject:
Receptors, Cell Surface.
Subject:
Nuclear receptors.
Subject:
Receptors, Cytoplasmic and Nuclear.
Subject:
Neurology - General
Edition Description:
Includes bibliographical references and index.
Series Volume:
8
Publication Date:
January 2000
Binding:
Hardcover
Language:
English
Illustrations:
Yes
Pages:
476
Dimensions:
11.28x8.88x1.08 in. 3.47 lbs.

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