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Organic Chemistry

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Synopses & Reviews

Publisher Comments:

Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the student's choice of an organic chemistry text.

The second edition refines and refocuses Organic Chemistry to produce a text that is even more student-friendly, coherent, and logical in its presentation than before.

Like the first, the second edition is built on three principles:

An explanatory approach, through which the reader is motivated to understand the subject and not just learn the facts;

A mechanistic approach, giving the reader the power to understand compounds and reactions never previously encountered;

An evidence-based approach, setting out clearly how and why reactions happen as they do, giving extra depth to the reader's understanding.

The authors write clearly and directly, sharing with the reader their own fascination with the subject, and leading them carefully from topic to topic. Their honest and open narrative flags pitfalls and misconceptions, guiding the reader towards a complete picture of organic chemistry and its universal themes and principles.

SUPPORT MATERIALS

The Companion Website (www.oup.com/uk/orc/bin/9780199270293), available to all adopters of the text, includes:

- 3D Organic Animations: Link to chemtube3d to view interactive 3D animations developed by the author

- Additional Chapters: Four chapters from the first edition that do not appear in the second

- Errata: Corrections to the book since publication

- End-of-Chapter Questions: A range of problems to accompany each chapter

- Figures in PowerPoint: Figures pre-inserted into PowerPoint for use in lectures and handouts

- Problems: Problems to accompany each chapter from the new edition of Organic Chemistry will be posted in the student area of the book's Companion Website throughout the year (April, June, and December 2012)

About the Author

Jonathan Clayden is a Professor of Organic Chemistry at the University of Manchester, where he and his research group work on the construction of molecules with defined shapes - in particular those where control of conformation and limitation of flexibility is important. Jonathan was awarded a BA (Natural Sciences) from Churchill College, Cambridge before completing his PhD with Stuart Warren, also at the University of Cambridge. He has been at the University of Manchester since 1994.

Nick Greeves is the Director of Teaching and Learning in the Department of Chemistry at the University of Liverpool. Nick is a Cambridge graduate, obtaining his PhD there in 1986 for work on the stereoselective Horner-Wittig reaction with Stuart Warren. He then held a Harkness Fellowship at the University of Wisconsin-Madison and at Stanford University, California, and a Research Fellowship at Cambridge University before joining Liverpool in 1989 where he is currently a Senior Lecturer.

Stuart Warren is a former lecturer in the Department of Chemistry at the University of Cambridge and Fellow of Churchill College, Cambridge. A graduate of Trinity College, Cambridge, Stuart completed his PhD at Cambridge with Malcolm Clark before carrying out post-doctoral research at Harvard University. He became a teaching fellow at Churchill College in 1971, and remained a lecturer and researcher at Cambridge until his retirement in 2006.

Table of Contents

1. What Is Organic Chemistry?

2. Organic Structures

3. Determining Organic Structures

4. Structure of Molecules

5. Organic Reactions

6. Nucleophilic Addition to the Carbonyl Group

7. Delocalization and Conjugation

8. Acidity, Basicity, and Pka

9. Using Organometallic Reagents to Make C-C Bonds

10. Nucleophilic Substitution at the Carbonyl Group

11. Nucleophilic Substitution at C=O with Loss of Carbonyl Oxygen

12. Equilibria, Rates, and Mechanisms

13. 1H NMR: Proton Nuclear Magnetic Resonance

14. Stereochemistry

15. Nucleophilic Substitution at Saturated Carbon

16. Conformational Analysis

17. Elimination Reactions

18. Review of Spectroscopic Methods

19. Electrophilic Addition to Alkenes

20. Formation and Reactions of Enols and Enolates

21. Electrophilic Aromatic Substitution

22. Conjugate Addition and Nucleophilic Aromatic Substitution

23. Chemoselectivity and Protecting Groups

24. Regioselectivity

25. Alkylation of Enolates

26. Reactions of Enolates with Carbonyl Compounds: The Aldol and Claisen Reactions

27. Sulfur, Silicon, and Phosphorus in Organic Chemistry

28. Retrosynthetic Analysis

29. Aromatic Heterocycles 1: Structures and Reactions

30. Aromatic Heterocycles 2: Synthesis

31. Saturated Heterocycles and Stereoelectronics

32. Stereoselectivity in Cyclic Molecules

33. Diastereoselectivity

34. Pericyclic Reactions 1: Cycloadditions

35. Pericyclic Reactions 2: Sigmatropic and Electrocyclic Reactions

36. Participation, Rearrangement, and Fragmentation

37. Radical Reactions

38. Synthesis and Reactions of Carbenes

39. Determining Reaction Mechanisms

40. Organometallic Chemistry

41. Asymmetric Synthesis

42. Organic Chemistry of Life

43. Organic Chemistry Today

Product Details

ISBN:
9780199270293
Author:
Clayden, Jonathan
Publisher:
Oxford University Press, USA
Author:
Warren, Stuart
Author:
Greeves, Nick
Subject:
Chemistry - Organic
Subject:
Chemistry | Organic Chemistry
Publication Date:
20120531
Binding:
TRADE PAPER
Language:
English
Illustrations:
3600 color line drawings
Pages:
1,264
Dimensions:
7.8 x 10.9 x 1.8 in 5.4 lb

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