Synopses & Reviews
With the completion of human genome sequencing, the field of proteomics has grown vital to biomedical research. Among the array of protocols developed to study the human proteome, many protocols examine proteins derived specifically from cell lines, body fluids or human tissues - not necessarily compatible with the full range of protein sources commonly used in the laboratory. Tissue Proteomics constitutes in one volume useful and innovative protocols developed specifically for the proteomic profiling of human tissues. A unique resource for researchers, Tissue Proteomics provides high-throughput gel-based techniques, microarrays and a number of other methods used in proteomic research, a field still in its early stages. This important book will prove indispensable to investigators of biomarker discovery and therapeutic response profiling, as well as those forging new paths in the fields of theranostics and personalized medicine.
Book News Annotation:
With drug discovery at (or at least near) the top of the list of
dynamic areas of life science research, especially since the
completion of human genome sequencing. Here contributors step up the
pace even more with specific instructions on protocols relating to
the proteomic profiling of human tissues. Topics include
high-throughput gel-based techniques, including those used to examine
the entire proteome within discrete pl fractions and complementary
techniques for the specific analysis of glycoproteins, mass
spectrometry techniques to use in identifying proteins, automated
laser capture dissection (as it is used with other techniques),
production and use of microarrays for the purpose of profiling
protein expression patterns in tissue samples, arrays using
tissue-derived antigens, reverse-array platforms,
commercially-designed arrays, and measurement of autoantibody
expression in tissues, including new methods for detecting
autoantibody expression.
Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)
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