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Inositol Phosphates & Derivatives: Synthesis, Biochemistry, & Therapeutic Potential

Inositol Phosphates & Derivatives: Synthesis, Biochemistry, & Therapeutic Potential Cover

 

Synopses & Reviews

Publisher Comments:

This new volume examines the synthesis, biochemistry, and pharmacological evaluation aspects of design compounds with therapeutic effects. Two overview chapters provide comprehensive background information on stereochemistry and nomenclature of inositol phosphates, basic biochemistry, synthetic challenges, and related pharmacology. Subsequent chapters describe novel methods of preparation, including the use of unusual starting materials and mediation by microorganisms, therapeutic potential and bioactivity, and structure-activity relationships.

Book News Annotation:

Key aspects of research on a group of compounds crucial to the transduction of information in living organisms are reviewed in 16 papers from a symposium at the American Chemical Society meeting in Washington, DC, in August 1990. Emphasizes the viewpoint of synthetic organic chemistry, but also notes the contributions from biochemistry and pharmacology.
Annotation c. Book News, Inc., Portland, OR (booknews.com)

Synopsis:

This new volume examines the synthesis, biochemistry, and pharmacological evaluation aspects of design compounds with therapeutic effects. Two overview chapters provide comprehensive background information on stereochemistry and nomenclature of inositol phosphates, basic biochemistry, synthetic challenges, and related pharmacology. Subsequent chapters describe novel methods of preparation, including the use of unusual starting materials and mediation by microorganisms, therapeutic potential and bioactivity, and structure-activity relationships.

Table of Contents

Biochemistry, Stereochemistry, and Nomenclature of the Inositol Phosphates

Phosphoinositides and Their Stimulated Breakdown

Enantiospecific Synthesis and Ca�]+-Release Activities of Some Inositol Polyphosphates and Their Derivatives

Synthesis of Inositol Polyphosphates and Their Derivatives

Synthesis of myo-Inositol Polyphosphates

Preparation of Optically Active myo-Inositol Derivatives as Intermediates for the Synthesis of Inositol Phosphates

Pharmacolotical Effects of D-myo-Inositol-1,2,6-Trisphosphate

Synthesis of New myo-Inositol Derivatives Containing Phosphate, Sulfate, and Sulfonamido Groups

Chemical Modifications of Inositol Trisphosphates: Tritiated, Fluorinated, and Phosphate-Tethered Analogues

Novel Routes to Inositol Phosphates Using Pseudomonas putida Oxidation of Arenes

Enantiospecific Synthesis of Inositol Polysphophates, Phosphatidylinositides, and Analogues from (-)-Quinic Acid

Synthesis and Complexation Properties of Inositol-Phosphates

Phosphorothioate Analogues of Phosphatidylinositol and Inositol 1,2-Cyclic Phosphate: Application to the Mechanism of Phospholipase C

Phosphorothioate Analogues of D-myo-Inositol 1,4,5-Trisphosphate: Chemistry and Biology

Synthesis and Biological Evaluation of Inositol Derivatives as Inhibitors of Phospholipase C

Synthesis and Biological Evaluation of Inositol Phospholipid Analogues

Product Details

ISBN:
9780841220867
Subtitle:
Synthesis, Biochemistry, and Therapeutic Potential
Publisher:
American Chemical Society
Author:
Allen B. Reitz
Author:
null, Allen B.
Location:
Washington, DC :
Subject:
Pharmacology
Subject:
Chemistry | Biological Chemistry
Edition Description:
Includes bibliographical references and indexes.
Series:
ACS symposium series ;
Series Volume:
9300463
Publication Date:
19910505
Binding:
Hardback
Grade Level:
College/higher education:
Illustrations:
10 figures
Pages:
235
Dimensions:
6 x 9.1 x 0.9 in 1.025 lb

Related Subjects

Health and Self-Help » Health and Medicine » Professional Medical Reference
Science and Mathematics » Chemistry » Biochemistry
Science and Mathematics » Materials Science » Textiles

Inositol Phosphates & Derivatives: Synthesis, Biochemistry, & Therapeutic Potential
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Product details 235 pages American Chemical Society - English 9780841220867 Reviews:
"Synopsis" by , This new volume examines the synthesis, biochemistry, and pharmacological evaluation aspects of design compounds with therapeutic effects. Two overview chapters provide comprehensive background information on stereochemistry and nomenclature of inositol phosphates, basic biochemistry, synthetic challenges, and related pharmacology. Subsequent chapters describe novel methods of preparation, including the use of unusual starting materials and mediation by microorganisms, therapeutic potential and bioactivity, and structure-activity relationships.
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