Hemodynamic monitoring is one of the major diagnostic tools available in the acute care setting to diagnose cardiovascular insufficiency and monitor changes over time in response to interventions. However, the rationale and efficacy of hemodynamic monitoring to affect outcome has come into question. We now have increasing evidence that outcome from critical illness can be improved by focused resuscitation based on existing hemodynamic monitoring, whereas non-specific aggressive resuscitation impairs survival. Thus, this book frames hemodynamic monitoring into a functional perspective wherein hemodynamic variables and physiology interact to derive performance and physiological reserve estimates that themselves drive treatment. This philosophy, as well as the limitations and applications of common and evolving hemodynamic measures and their focused use in the care of critically ill patients are discussed, relevant to one underlying truth: No monitoring device, no matter how simple or sophisticated, will improve patient-centered outcomes useless coupled to a treatment which, itself, improves outcome.

Michael R. Pinsky, MD is a professor of Critical Care medicine, Bioengineering and Anaesthesiology at the University of Pittsburgh and Dr hc from the University of Paris (La Sorbonne). He is considered an expert in hemodynamic monitoring, cardiovascular and pulmonary physiology and the treatments of cardio-respiratory diseases, including septic shock, ARDS and transplantation.Didier Payen, MD is a professor and chairman of Anaesthesiology and Critical Care Medicine at Laribosiere Hospital, Paris and the president of the European Society of Intensive care Medicine. He is considered an expert in hemodynamic monitoring, organ transplantation, nitric oxide metabolism and treatment and cardiovascular physiology.

Introduction.- Therapeutic goals.- Limits and Applications of Hemodynamic Monitoring.- Measurement of Oxygen Derived Variables and Cardiac Performance.- Assessment of Fluid Responsiveness.- Development of Treatment Algorithms.- Index.