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General, Organic, and Biological Chemistry: An Integrated Approach with Masteringchemistry(r)

General, Organic, and Biological Chemistry: An Integrated Approach with Masteringchemistry(r) Cover

 

Synopses & Reviews

Publisher Comments:

Drawing on 20 years of teaching allied health and pre-professional students, authors Laura Frost and Todd Deal have created this innovative new text for your GOB chemistry course.  General, organic, and biological chemistry topics are integrated throughout each chapter in a manner that immediately relates chemistry to your future allied health career and everyday life. General, Organic, and Biological Chemistry: An Integrated Approach with MasteringChemistry® introduces the problem-solving skills you will need to assess situations critically on the job. Unique guided-inquiry activities are incorporated after each chapter, guiding you through an exploration of the information to develop chemical concepts, and then apply the developed concept to further examples.

About the Author

Laura D. Frost is an Associate Professor of Chemistry at Georgia Southern University, where she has taught chemistry to allied health students since 2000. She received her bachelor’s degree in chemistry from Kutztown University and a Ph.D. in chemistry with a biophysical focus from the University of Pennsylvania.

Professor Frost is actively engaged in the teaching and learning of chemistry and uses a guided inquiry approach in her classes. Dr. Frost is a member of the American Chemical Society and its Chemical Education division and the Biophysical Society. In 2007, she was honored with the Regent’s Award for the Scholarship of Teaching and Learning by the University System of Georgia and was inducted into the Regent’s Hall of Fame for Teaching Excellence. She is an advocate for increased student learning in science, technology, engineering, and mathematics (STEM) disciplines using guided inquiry and has spoken at numerous conferences and workshops on this topic.

Todd S. Deal  received his B.S. degree in chemistry in 1986 from Georgia Southern College (now University) in Statesboro, Georgia, and his Ph.D. in chemistry in 1990 from The Ohio State University. He joined the faculty of his undergraduate alma mater in 1992, where he currently serves as Director of the Office of Student Leadership and Civic Engagement.

Professor Deal has taught chemistry to allied health and preprofessional students for 20 years. In 1994, he was selected Professor of the Year by the students at Georgia Southern University. Professor Deal is also the recipient of the Allen E. Paulson College of Science and Technology’s Award for Excellence in Teaching (2003), the Georgia Southern University Award for Excellence in Contributions to Instruction (2003), and the Allen E. Paulson College of Science and Technology’s Award for Excellence in Service (2006).

Karen Timberlake is Professor Emerita of chemistry at Los Angeles Valley College, where she taught chemistry for allied health and preparatory chemistry for 36 years. Professor Timberlake has been writing chemistry textbooks for 33 years. She is known for her strategic use of pedagogical tools that promote student success in chemistry and the application of chemistry to real-life situations. More than one million students have learned chemistry using texts, laboratory manuals, and study guides written by Karen Timberlake.

Table of Contents

Chapter 1:  Chemistry:  It’s All About “Stuff”

1.1    “Stuff” is Matter

Matter:  Mass and Volume

Math Matters – Metric Units and Prefixes

States of Matter

1.2    Gas Behavior – An Introduction to the Behavior of Matter

Gases and Pressure

Pressure and Volume – Boyle’s Law

Boyle’s Law and Breathing

Math Matters – Significant Figures and Rounding Calculator Results

Gases and Temperature

Temperature and Volume – Charles’s Law

1.3    Classifying Matter : Mixture or Pure Substance

Mixtures

Pure Substances

1.4    Elements, Compounds, and the Periodic Table

Compounds

1.5    How Matter Changes

Physical Change

Chemical Reaction

Chemical Equations

Summary

Key Terms

Important Equations

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 2

Chapter 2:  Atoms, Radioactivity, and Ions

2.1    The Atom and Subatomic Particles

Charges

Subatomic Particles

Structure of an Atom

2.2    Atomic Number and Mass Number

Atomic Number

Mass Number

2.3    Isotopes and Atomic Mass

Atomic Mass

2.4    Measuring Atoms: The Mole

Math Matters – Scientific Notation

Avogadro’s Number

2.5    Electron Arrangements

2.6    Radioactivity and Radioisotopes

Types of Radiation

2.7    Nuclear Equations and Radioactive Decay

Alpha Decay

Beta Decay

Gamma Decay

Producing Radioactive Isotopes

2.8    Radiation Units and Half-Lives

Radioactivity Units

Half Life

2.9    Medical Applications for Radioisotopes

Summary

Key Terms

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 3

Chapter 3:  Compounds: Putting Particles Together

3.1    The Octet Rule

3.2    In Search of an Octet Part 1: Ion Formation

Trends in Ion Formation

Naming Ions

Important Ions in the Body

3.3    Ionic Compounds – Give and Take

Formulas of Ionic Compounds

Naming Ionic Compounds

3.4    In Search of an Octet Part 2: Covalent Bonding

Formulas and Structures of Covalent Compounds

Naming Covalent Compounds

3.5    Getting Covalent Compounds into Shape

    Determining the Shape of a Molecule

Lone Pairs and their Effect on Molecular Shape

Molecular Shape of Larger Molecules

3.6    Electronegativity and Molecular Polarity

    Electronegativity

    Molecular Polarity

Summary

Key Terms

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 4

Chapter 4:  Introduction to Organic Compounds

4.1    Alkanes – The Simplest Organic Compounds

Straight chain alkanes

Cycloalkanes

4.2    Representing the Structures of Organic Compounds

Condensed structural formulas

Skeletal structures

Cyclic alkanes

4.3    Fatty Acids — Biological Hydrocarbons

Alkanes are non-polar compounds

Structure and polarity of fatty acid molecules

Unsaturated fatty acids

Fatty acids in our diet

4.4    Families of Organic Compounds – Functional Groups

Unsaturated hydrocarbons – Alkenes, Alkynes, and Aromatics

Alkenes

Alkynes

Aromatics

4.5    Isomerism in Organic Compounds, Part 1

Structural isomers

Conformational isomers

Nomenclature of simple compounds

Branched chain alkanes

Haloalkanes

Cycloalkanes

4.6    Isomerism in Organic Compounds, Part 2

Cis/Trans isomerism in cycloalkanes

Cis/Trans isomerism in alkenes

Stereoisomerism in chiral molecules

The consequences of chirality

Summary

Key Terms

Summary of Reactions

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 5

Chapter 5:   Carbohydrates:  Life’s Sweet Molecules

5.1    Carbohydrates

5.2    Monosaccharide Structure

    Functional Groups in Monosaccharides – Alcohol, Aldehyde, and Ketone

        Alcohol

        Aldehyde

        Ketone

Stereochemistry in Monosaccharides

Multiple Chiral Centers

Representing Stereoisomers – The Fischer Projection

Stereoisomers That are Not Enantiomers

Some Important Monosaccharides

5.3    Oxidation and Reduction Reactions

    Oxidation and Reduction

    Monosaccharides and Redox

5.4    Ring Formation – The Truth about Monosaccharide Structure

5.5    Disaccharides

Condensation and Hydrolysis – Forming and Breaking Glycosidic Bonds

Naming Glycosidic Linkages

Some Important Disaccharides

Maltose

Lactose

Sucrose   

Relative Sweetness of Monosaccharides and Sucrose

5.6    Polysaccharides

Storage Polysaccharides

Amylose and Amylopectin

Glycogen

Structural Polysaccharides

Cellulose

Chitin

5.7    Carbohydrates and Blood

ABO Blood Groups

Heparin

Summary

Key Terms

Summary of Reactions

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 6

Chapter 6: Intermolecular Forces: State Changes, Solubility, and Cell Membranes

6.1    Types of Intermolecular Forces

London Forces

Dipole-Dipole Attractions

Hydrogen Bonding

Ion-Dipole Attraction: A Similar Force

6.2    Intermolecular Forces and Solubility

The Golden Rule of Solubility

Applying the Golden Rule: To Non-polar Compounds

Applying the Golden Rule: To Polar Compounds

Applying the Golden Rule: To Ionic Compounds

The Unique Chemistry of Soap

6.3  Intermolecular Forces and Changes of State

Heat and Intermolecular Forces

Boiling Points and Alkanes

The Unusual Behavior of Water

6.4  Fats, Oils, and Margarine – Solid to Liquid and Back Again

Fats

Oils

Margarine: Changing the Liquid to a Solid

Trans Fats

6.5  Intermolecular Forces and the Cell Membrane

A Quick Look at Phospholipids

The Cell Membrane is a Bilayer

Cholesterol in Membranes

Summary

Key Terms

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 7

Chapter 7: Solution Chemistry:  How Sweet is Your Tea?

7.1    Solutions are Mixtures

Phases of Solutes and Solvents

Colloids and Suspensions 

7.2    Formation of Solutions

Factors Affecting Solubility and Saturated Solutions

Solubility and Temperature

Solubility and Pressure – Henry’s Law

7.3    Chemical Equations for Solution Formation – Electrolytes

Strong Electrolytes

Nonelectrolytes

Weak Electrolytes

Ionic Solutions and Equivalents

7.4    Concentration

Milliequivalents per Liter (mEq/L)

Millimoles per Liter (mmol/L) and Molarity (M)

Percent (%)

Math Matters – Percent

    Mass / volume Percent (% m/v)

    Relationship to Other Common Units

    Mass / mass Percent (% m/m)

    Volume / volume Percent (% v/v)

Parts per Million (ppm) and Parts per Billion (ppb)

7.5    Dilution

7.6    Osmosis and Diffusion

Osmosis

Diffusion and Dialysis

7.7    Transport Across Cell Membranes

Diffusion, Facilitated Transport, and Active Transport

Summary

Key Terms

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 6

Chapter 8:  Acids, Bases, and the Building Blocks of Life

8.1    Acids and Bases – Definitions

Acids

Bases

8.2    Strong Acids and Bases

Neutralization

Antacids

8.3    Chemical Equilibrium

The Equilibrium Constant, Keq

Effect of Concentration on Equilibrium

Effect of Temperature on Equilibrium

8.4    Weak Acids and Bases

    Equilibrium

The Equilibrium Constant Ka

    Conjugate Acids and Bases

8.5    pH and the pH scale

    The Autoionization of Water, Kw

    [H3O+], [OH-], and pH

    Measuring pH

Math Matters – Logarithms and Inverse Logarithms

    Calculating pH

    Calculating [H3O+]

8.6    pKa 

The relationship between pH and pKa

8.7    Amino Acids:  Common Biological Weak Acids

8.8    Buffers:  An Important Property of Weak Acids and Bases

    Maintaining Physiological pH with Bicarbonate Buffer:  Homeostasis

        Changes in Ventilation Rate

        Changes in Metabolic Acid Production

Summary

Key Terms

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 9

Chapter 9:  Proteins – Amides at Work

9.1 Amino Acids – A second look

Amino Acid Structure

Amino Acid Classification

9.2    Protein Formation

Condensation Reaction of Amino Acids

Amide or Peptide, Which Is It?

9.3    Protein Structure

Primary Structure – N-terminus & C-terminus

Secondary structure

     a-helix

    b-strands and sheets

Tertiary Structure

Quaternary Structure

9.4  Protein Denaturation

9.5  Sample Proteins

    Hemoglobin

    Collagen

Summary

Key Terms

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 10

Chapter 10:  Enzymes – Nature’s Chemists

10.1    Enzymes and Their Substrates

Active site

Catalysis

10.2    Enzyme Activity

10.3     Reaction Energetics and Thermodynamics

10.4      Reaction Energy Diagrams

10.5     Activation Energy (Ea)

Enzymes Lower Activation Energy

Summary

Key Terms

Additional Problems

    Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 11

Chapter 11:  Nucleic Acids – Big Molecules with a Big Role

11.1    Components of Nucleic Acids

    Nitrogenous Bases

    Ribose and Deoxyribose

    Condensation of the Components

    Naming Nucleotides

11.2    Nucleic Acid Formation

    Primary Structure:  Nucleic Acid Sequence

11.3      DNA

Secondary Structure:  Complementary Base Pairing

Tertiary Structure:  Chromosomes

11.4      RNA and Protein Synthesis

    RNA Types

    Messenger RNA and Transcription

    Ribosomal RNA and the Ribosome

    Transfer RNA and Translation

11.5     Putting It Together:  The Genetic Code and Protein Synthesis

The Genetic Code

Protein Synthesis

    Transcription

    tRNA Activation

    Translation

    Termination

11.6     Genetic Mutations

11.7     Viruses

    Retroviruses

    HIV-1 and AIDS

11.8    Recombinant DNA Technology

Therapeutic Proteins

Genetically Modified Crops

Genetic Testing

Nuclear Transplantation – Cloning an Organism

Summary

Key Terms

Additional Problems

Challenge Problems

Answers to Odd Numbered Problems

Looking Ahead – GI problems for Chapter 12

Chapter 12:  Food As Fuel – A Metabolic Overview

12.1  Overview of Metabolism

Where in the Cell?

12.2  Metabolically Relevant Nucleotides

 ATP / ADP

NADH / NAD+ and FADH2 / FAD

Acetyl Coenzyme A / Coenzyme A

12.3  Digestion – From Fuel Molecules to Building Blocks

Carbohydrates

Fats

Proteins  

12.4  Glycolysis – From Building Blocks to Common Metabolites

Chemical Reactions in Glycolysis

Regulation of Glycolysis

Fates of Pyruvate

Aerobic Conditions

Anaerobic Conditions

Glycogen

Fructose

12.5  The Citric Acid Cycle – Central Processing

    Reactions of the Citric Acid Cycle   

Citric Acid Cycle Summary

12.6  Electron Transport and Oxidative Phosphorylation

    Electron Transport

Oxidative Phosphorylation

Thermogenesis – Uncoupling ATP Synthase

12.7  ATP Production

    Counting ATP from One Glucose

Glycolysis

Oxidation of Pyruvate

Citric Acid Cycle

Total ATP from Glucose Oxidation

12.8  Other Fuel Choices

Energy from Fatty Acids

The Beta Oxidation Cycle

Cycle Repeats and ATP Production

Too Much Acetyl CoA - Ketosis

Energy from Amino Acids

Putting It Together:  Linking the Pathways

Summary

Key Terms

Summary of Reactions

Additional Problems

Challenge Problems

Answers to Odd Numbered Problems

 

Product Details

ISBN:
9780321706195
Subtitle:
An Integrated Approach Plus MasteringChemistry with eText -- Access Card Package
Publisher:
Prentice Hall
Author:
Frost, Laura D.
Author:
Timberlake, Karen C.
Author:
Deal, S. Todd
Author:
Deal, Todd S.
Subject:
Chemistry - General
Copyright:
Edition Description:
Trade paper
Series:
MasteringChemistry Series
Publication Date:
January 2010
Binding:
Hardback
Grade Level:
College/higher education:
Language:
English
Pages:
512
Dimensions:
11.1 x 8.6 x 1 in 1311 gr

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