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Power Laws, Scale-Free Networks and Genome Biology (Molecular Biology Intelligence Unit)

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Power Laws, Scale-Free Networks and Genome Biology (Molecular Biology Intelligence Unit) Cover

 

Synopses & Reviews

Publisher Comments:

Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks of biological organization in the post-genomic era. The chapters in the book not only describe the interesting mathematical properties of biological networks but moves beyond phenomenology, toward models of evolution capable of explaining the emergence of these features. The collection of chapters, contributed by both physicists and biologists, strives to address the problems in this field in a rigorous but not excessively mathematical manner and to represent different viewpoints, which is crucial in this emerging discipline. Each chapter includes, in addition to technical descriptions of properties of biological networks and evolutionary models, a more general and accessible introduction to the respective problems. Most chapters emphasize the potential of theoretical systems biology for discovery of new biological phenomena.

Table of Contents

The Architecture of the Cell: Scaling and Hierarchy in Cellular Networks.- Classification of Scale-Free Networks.- Wide Spread Occurrence of Power Law Behavior in Genomic Biology.- Detection of Topological Patterns in Protein-Binding and Transcription Regulation Networks.- The Structure of Metabolic and Protein Interaction Networks: Design, History, or (mere) Chemistry?.- Protein-Protein Interaction Networks.- The Society of Genes: Networks of Functional Links Between Genes from Comparative Genomics.- Emergence of Patterns in Gene Networks.- Mathematical Modeling of Genome Evolution: Origin of the Ubiquitous Power Law Distributions.- Expanding Protein Universe and its Origin from the Biological Big Bang.

Product Details

ISBN:
9780387258836
Author:
Koonin, Eugene V.
Publisher:
Koonin, E.V.
Author:
Karev, Georgy P.
Author:
Karev, Georgy
Author:
Karev, G.
Author:
Wolf, Yuri
Author:
Wolf, Yuri I.
Subject:
Biophysics
Subject:
Mathematical models
Subject:
Algorithms
Subject:
Life Sciences - Biophysics
Subject:
Life Sciences - Biochemistry
Subject:
Life Sciences - Biology - General
Subject:
Genomics
Subject:
Computational Biology
Subject:
Life Sciences - Genetics & Genomics
Subject:
Life Sciences - Biology - Molecular Biology
Subject:
Biophysics and Biological Physics
Subject:
Bioinformatics
Subject:
Biochemistry, general
Subject:
Microbial Genetics and Genomics
Subject:
Proteomics
Subject:
Physics, general <P>The first such compendium in the field</P> <P>Contributed by leading researchers in the field</P> <P>Balanced coverage of the emerging field of Theoretical Systems Biology, accessibility to researchers with limited mathematical backgro
Subject:
Physics
Subject:
Physics-General
Copyright:
Edition Number:
1
Edition Description:
Book
Series:
Molecular Biology Intelligence Unit
Publication Date:
March 2006
Binding:
HARDCOVER
Language:
English
Illustrations:
Y
Pages:
274
Dimensions:
234 x 156 mm 635 gr

Related Subjects

Health and Self-Help » Health and Medicine » Medical Specialties
Science and Mathematics » Biology » Biophysics
Science and Mathematics » Biology » Cytology and Cell Biology
Science and Mathematics » Biology » General
Science and Mathematics » Biology » Genetics
Science and Mathematics » Biology » Molecular
Science and Mathematics » Chemistry » Biochemistry
Science and Mathematics » Physics

Power Laws, Scale-Free Networks and Genome Biology (Molecular Biology Intelligence Unit) New Hardcover
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Product details 274 pages Koonin, E.V. - English 9780387258836 Reviews:
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