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Structural Biology: Practical NMR Applications

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Structural Biology: Practical NMR Applications Cover

 

Synopses & Reviews

Publisher Comments:

Over the years since NMR was first applied to solve problems in structural biology, both NMR instrument hardware and methodology have been dramatically developed. This book offers a much-needed update to the 2005 first edition, and will be of critical importance to those who routinely use NMR to study various biological systems as well as a textbook. Thus, the book is organized with experimentalists in mind, whether they are instructors or students. For those who have minimal background in NMR structural biology, this book will provide fresh perspective and insight; those who are already well-versed in NMR research will find cutting edge updates and new information and methods that are useful to their research. Because understanding fundamental principles and concepts of NMR spectroscopy is essential for the application of NMR methods to research projects, the book begins with an introduction to basic NMR principles. Next, NMR instrumentation is discussed starting with hardware components. Topics include magnetic field homogeneity and stability, signal generation and detection, probe circuits, cryogenic probe, analog-to-digital conversion, and test equipment. A typical specification for a NMR spectrometer is also included in the chapter. There is also a chapter covering NMR sample preparation, a process that is often the bottleneck for the success of the NMR projects. Several routine strategies for preparing samples, especially for macromolecules as well as complexes are dealt with in detail.

Synopsis:

The revised 2nd edition of this book explores NMR development and applications in biological systems. The coverage includes improvements in NMR hardware and methodology, instrument setup, data acquisition and data processing using offline programs.

Synopsis:

This 2nd edition begins with an overview of NMR development and applications in biological systems. It describes recent developments in instrument hardware and methodology. Chapters highlight the scope and limitation of NMR methods. While detailed math and quantum mechanics dealing with NMR theory have been addressed in several well-known NMR volumes, chapter two of this volume illustrates the fundamental principles and concepts of NMR spectroscopy in a more descriptive manner. Topics such as instrument setup, data acquisition, and data processing using a variety of offline software are discussed. Chapters further discuss several routine stategies for preparing samples, especially for macromolecules and complexes. The target market for such a volume includes researchers in the field of biochemistry, chemistry, structural biology and biophysics.

Table of Contents

Chapter 1: Basic Principles of NMR Chapter 2: Instrumentation Chapter 3: NMR Sample Preparation Chapter 4: Practical Aspects Chapter 5: Multi-Dimensional Heteronuclear NMR Experiments Chapter 6: Studies Of Small Biological Molecules Chapter 7: Protein Structure Determination From NMR Data Chapter 8: Protein Dynamics Chapter 9: NMR-based Metabolomics

Product Details

ISBN:
9781461439639
Author:
Teng, Quincy, Quincy
Publisher:
Springer
Author:
Teng, Quincy
Subject:
Molecular biology
Subject:
Molecular Medicine
Subject:
Biomedicine general
Subject:
Biophysics and Biological Physics
Subject:
Biochemistry, general
Subject:
Biotechnology
Subject:
Health and Medicine-General
Copyright:
Edition Description:
2nd ed. 2012
Publication Date:
20120831
Binding:
HARDCOVER
Language:
English
Pages:
445
Dimensions:
235 x 155 mm

Related Subjects

Health and Self-Help » Health and Medicine » General
Health and Self-Help » Health and Medicine » General Medicine
Science and Mathematics » Biology » Biophysics
Science and Mathematics » Biology » General
Science and Mathematics » Biology » Microbiology
Science and Mathematics » Biology » Molecular
Science and Mathematics » Chemistry » Biochemistry
Science and Mathematics » Physics

Structural Biology: Practical NMR Applications New Hardcover
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Product details 445 pages Springer - English 9781461439639 Reviews:
"Synopsis" by , The revised 2nd edition of this book explores NMR development and applications in biological systems. The coverage includes improvements in NMR hardware and methodology, instrument setup, data acquisition and data processing using offline programs.
"Synopsis" by , This 2nd edition begins with an overview of NMR development and applications in biological systems. It describes recent developments in instrument hardware and methodology. Chapters highlight the scope and limitation of NMR methods. While detailed math and quantum mechanics dealing with NMR theory have been addressed in several well-known NMR volumes, chapter two of this volume illustrates the fundamental principles and concepts of NMR spectroscopy in a more descriptive manner. Topics such as instrument setup, data acquisition, and data processing using a variety of offline software are discussed. Chapters further discuss several routine stategies for preparing samples, especially for macromolecules and complexes. The target market for such a volume includes researchers in the field of biochemistry, chemistry, structural biology and biophysics.
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