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Modern Methods in Crop Protection Researchby Peter (edt) Jeschke
Synopses & Reviews
This handbook and ready reference highlights a couple of basic aspects of recently developed new methods in modern crop protection research, authored by renowned experts from major agrochemical companies. Organized into four major parts that trace the key phases of the compound development process, the first section addresses compound design, while the second covers newly developed methods for the identification of the mode of action of agrochemical compounds. The third part describes methods used in improving the bioavailability of compounds, and the final section looks at modern methods for risk assessment. As a result, the agrochemical developer will find here a valuable toolbox of advanced methods, complete with first-hand practical advice and copious examples from current industrial practice.
About the Author
Peter Jeschke leads the global research group on insecticide chemistry at Bayer CropScience, based in Monheim (Germany).
Wolfgang Kramer gained his PhD in organic chemistry from the TU Stuttgart (Germany) in 1968, before moving to Bayer Plant Protection as lab leader in plant protection research in 1970. Between 1984 and 1990 he was Head of Global Chemistry Fungicides, and Head of Insecticides thereafter. Dr. Kramer has over 250 patent applications and publications to his name.
Ulrich Schirmer gained his PhD in organic chemistry from Stuttgart University (Germany) in 1973, and subsequently carried out his postdoc at Paris-Orsay (France). He joined BASF in 1974, eventually becoming Senior Vice President responsible for plant protection research for chemical synthesis, process development and biological R&D. Dr. Schirmer has over 100 patent applications and publications to his name.
Matthias Witschel gained his PhD in 1994 at the University of Erlangen-Nurnberg (Germany). After his post-doctoral stay as a Feodor-Lynen-Fellow in the group of Prof. B. M. Trost, Stanford (USA), he started in 1996 at BASF in herbicide research, where he is now the global head of herbicide crop protection research, based in Ludwigshafen. Dr. Witschel is the author and co-author of over 100 patents and scientific publications.
Table of Contents
METHODS FOR THE DESIGN AND OPTIMIZATION OF NEW ACTIVE INGREDIENTS
High Throughput Screening in Agrochemical Research
Molecular Modeling in Agricultural Research
Quantumchemical Methods in Design of Agrochemicals
The Unique Role of Halogen Substituents in the Design of Modern Crop Protection Compounds
NEW METHODS FOR THE IDENTIFICATION OF THE MODE OF ACTION OF ACTIVE INGREDIENTS
RNA interference (RNAi) Technology for Functional Genomics Studies and as Tool for Crop Protection
Fast Identification of the Mode of Action of Herbicides by DNA Chips
Electrophysiology for the Detection of Fast Acting Insecticides
New Targets for Fungicides
NEW METHODS FOR THE IMPROVEMENT OF THE BIOAVAILABILITY OF ACTIVE INGREDIENTS
New formulation developments
Polymorphism and the Organic Solid State: Influences on (Bio)performance and Product Optimization
Application of Abraham descriptors and LFER analysis
MODERN METHODS FOR RISK ASSESSMENT
Ecological Modeling in Pesticide Risk Assessment: Chances and Challenges
Metabolomics in Screening
Toxicological Testing of New Pesticide Active Ingredients: Impact of Hazard-Based Regulations
Endocrine Disruption Definition and Screening Aspects in the Light of the European Crop Protection Law
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