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Cellular Adhesion: Molecular Definition to Therapeutic Potentialby Brian W. Metcalf
Synopses & Reviews
The books in this acclaimed series provide integrated, critical surveys of topics of current interest to the pharmaceutical industry. Cellular Adhesion: Molecular Definition to Therapeutic Potential covers the molecular definition of adhesion molecule structure and function, the biological consequences of cellular adhesion, and the therapeutic potential of targeting adhesion molecules.
Book News Annotation:
Describes recent advances in the understanding of some processes related to the adhesion of a cell to a surface that may open opportunities for developing new therapeutics for a variety of diseases. Covers the molecules involved in the processes, the biological consequences of several adhesive interactions, and some initial therapeutic approaches to antagonizing adhesion. The 16 papers were presented at a symposium in Philadelphia in October 1992.
Annotation c. Book News, Inc., Portland, OR (booknews.com)
Table of Contents
Molecular Definition-Adhesion Molecule Structure and Function: Integrin Modulating Factor and the Regulation of Leukocyte Integrins; S.E. Wright. Structure-Function Aspects of Selectin-Carbohydrate Interactions; L.A. Lasky, et al. Recognition of Cell Surface Carbohydrates by C-Type Animal Lectins; W.I. Weiss. Biological Consequences of Cellular Adhesion: Effects of Shear Stress on Leukocyte Adhesion; O. Abbassi, et al. Blockade of Leukocyte Adhesion in In vivo Models of Inflamation; L. Flaherty, et al. Lung Inflamation and Adhesion Molecules; M.S. Mulligan, P.A. Ward. Targeting Adhesion Molecules-Therapeutic Potential: The Pathological Consequences of Bacterial Adhesion to Medical Devices; J.W. Costerton. Peptide Mimetics as Adhesion Molecule Antagonists; J. Samanen, et al. 8 additional articles. Index.
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