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Interpretation & Extrapolation of Reproductive Data to Establish Human Safety Standards

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Interpretation & Extrapolation of Reproductive Data to Establish Human Safety Standards Cover

 

Synopses & Reviews

Publisher Comments:

This monograph focuses on extrapolating data from animal reproduction studies to assess exposure levels acceptable for human reproduction which are consistent with the maintenance of public health. The interpretation and extrapolation of animal data for predicting human health effects from reproductive toxicants is a complex process with many uncertainties. This document attempts to outline some of the factors involved in the process, taking into account biological responses relevant to the test compound in experimental animals and humans. The guidelines for reproductive toxicity tests in different countries are summarized and a proposal for international harmonization is presented. The strengths and limitations of the test systems employed are also discussed. The monograph is intended for individuals interested or involved in safety assessment of chemicals.

Book News Annotation:

Outlines some of the factors involved in the process, taking into account biological responses relevant to the test compound in experimental animals and humans. Strengths and limitations of test systems and the harmonization of international guidelines are also discussed. No index.
Annotation c. Book News, Inc., Portland, OR (booknews.com)

Product Details

ISBN:
9780387969626
Author:
Khera, K. Ed
Publisher:
Springer
Author:
Clegg, D.J.
Author:
Khera, K.S.
Author:
Grice, H. C.
Location:
New York :
Subject:
Toxicology
Subject:
Health Risk Assessment
Subject:
Reproduction
Subject:
Reproductive toxicology
Subject:
Teratogens.
Subject:
Toxicology -- standards.
Subject:
Health and Medicine-Medical Specialties
Subject:
Pharmacology
Subject:
Pharmacology/Toxicology
Subject:
Cell biology
Subject:
Anthropology
Subject:
Pharmacy
Edition Description:
Softcover reprint of the original 1st ed. 1989
Series:
Current issues in toxicology
Series Volume:
13
Publication Date:
19890631
Binding:
TRADE PAPER
Language:
English
Illustrations:
Yes
Pages:
145
Dimensions:
235 x 155 mm 235 gr

Related Subjects

Health and Self-Help » Health and Medicine » Medical Specialties
Health and Self-Help » Health and Medicine » Pharmacology
Science and Mathematics » Biology » Cytology and Cell Biology
Science and Mathematics » Physics » General

Interpretation & Extrapolation of Reproductive Data to Establish Human Safety Standards New Trade Paper
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Product details 145 pages Springer-Verlag New York, Incorporated - English 9780387969626 Reviews:
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