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Endocrine Therapy for Breast Cancer

by and

Endocrine Therapy for Breast Cancer Cover

 

Synopses & Reviews

Publisher Comments:

Because of the predominant role estrogens play in the development of breast cancer and the limited effectiveness of tamoxifen therapy, more selective therapeutics targeting estrogen signaling have been developed: selective estrogen receptor modulators (SERMs), selective estrogen receptor downregulators (SERDs), and a third generation of drugs that inhibit the aromatase required for estrogen biosyntheses. The authors examine clinical and translational research results from studies of these endocrine therapies and chemotherapies in pre- and postmenopausal women with early and advanced breast cancer. Advances in Endocrine Therapy of Breast Cancer provides guidance on promising new therapeutics and treatment combinations based on compelling clinical evidence.

Book News Annotation:

Estrogen is predominant in the development of breast cancer, and efforts are under way to develop effective therapies targeting estrogen signaling. The result of the July 2003 Gleneagles Conference, these papers and transcripts of panel discussions evaluate the clinical pharmacology of selective estrogen receptor modulators (SERMs), selective estrogen receptor downregulators (SERDs), and aromatase inhibitors (AIs), They address endocrine therapy in post- and pre- menopausal women, the role of chemotherapy, chemoprevention and the biology of premalignant lesions, estrogen-induced carcinogenesis, the use of SERMs and AIs in clinical trials, and new therapeutic approaches based on emerging knowledge of the biology of breast cancer. Each paper includes references.
Annotation 2004 Book News, Inc., Portland, OR (booknews.com)

Product Details

ISBN:
9780824722289
Editor:
Ingle, James N.
Publisher:
CRC Press
Editor:
Ingle, James N.
Author:
Ingle, James N.
Author:
Dowsett, Mitchell
Author:
Ingle, Ingle N.
Subject:
Breast
Subject:
Diseases - Breast Cancer
Subject:
Gynecology & Obstetrics
Subject:
Cancer
Subject:
Oncology
Subject:
Breast -- Cancer -- Endocrine aspects.
Subject:
Breast Neoplasms -- drug therapy.
Subject:
Health and Medicine-Medical Specialties
Copyright:
Series:
Basic and Clinical Oncology
Series Volume:
30
Publication Date:
20040731
Binding:
Hardcover
Language:
English
Illustrations:
Y
Pages:
350
Dimensions:
9.28x6.20x.73 in. 1.46 lbs.

Related Subjects

Health and Self-Help » Health and Medicine » Medical Dictionaries and Encyclopedia
Health and Self-Help » Health and Medicine » Medical Specialties
Health and Self-Help » Health and Medicine » Pharmacology

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Product details 350 pages Marcel Dekker - English 9780824722289 Reviews:
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