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Other titles in the Fundamental and Clinical Cardiology series:
Fundamental and Clinical Cardiology #3: Molecular and Cellular Biology of the Allergic Responseby I. Levinson A
Synopses & Reviews
Providing a thorough overview of the fundamental elements of the human allergic immune response, this up-to-date reference focuses on the unique molecular and cellular features of the IgE-mediated immune response-relating these features to current knowledge of the immune response to protein antigens. Written by over 20 internationally renowned experts, Molecular and Cellular Biology of the Allergic Response ??describes T- and B-cell development and activation ??examines important genetic and structural features of the major histocompatibility complex ??details antigen processing and presentation ??explores the molecular and cellular biology of mast cells and basophils ??analyzes the processes underlying the synthesis of IgE in humans ??explains the cellular components and soluble factors that mediate IgE inflammation ??investigates the molecular characterization and immune recognition of allergenic peptides ??and more!
Book News Annotation:
An examination of IgE-mediated immune responses within the context of the current knowledge of immune mechanisms. The volume is divided into two parts. Part I deals with the essential ingredients of immune responsiveness and covers the molecular biology of T- and B-cell differentiation and activation, the molecular genetics of the major histocompatibility complex, and antigen processing and presentation. Part II provides an expanded look at how these processes give rise to an IgE-mediated immune response and how the unique properties of IgE, its cellular receptor, and the cells that bear this receptor render this molecule a potent inflammatory activator. It also deals with how this information can be harnessed to develop more rational treatment strategies for allergic disease.
Annotation c. Book News, Inc., Portland, OR (booknews.com)
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