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Protocols for Oligonucleotide Conjugates: Synthesis & Analytical Techniques

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Protocols for Oligonucleotide Conjugates: Synthesis & Analytical Techniques Cover

 

Synopses & Reviews

Publisher Comments:

You will easily synthesize and analyze oligonucleotide conjugates by following the step-by-step protocols presented in this volume. These techniques are widely used by all molecular biologists and antisense researchers and find special application by pharmacologists working in new drug development and quality assurance assay.

Book News Annotation:

Leading researchers provide the latest protocols for synthesizing oligonucleotide conjugates and explain the latest techniques for analyzing them. These techniques are widely used by pharmaceutical companies as part of the permit process for new drugs. They are also useful to molecular biologists and antisense researchers. Each protocol includes an introduction, a list of materials (including suppliers), step-by-step instructions, and notes for avoiding pitfalls and achieving the best results.
Annotation c. Book News, Inc., Portland, OR (booknews.com)

Table of Contents

Protecting Groups in Oligonucleotide Synthesis Incorporation of Modified Bases into Oligonucleotides Functionalization of Oligonucleotides with Amino Groups and Attachment of Amino Specific Reporter Groups Functionalization of Oligonucleotides by the Incorporation of Thio-Specific Reporter Groups Postsynthesis Functionalization of Oligonucleotides Oligonucleotide-Enzyme Conjugates Oligonucleotides Containing Degenerate Bases: Synthesis and Uses Synthesis of [15N]-Labeled DNA Fragments Analysis and Purification of Synthetic Oligonucleotides by High Performance Liquid Chromatography Sequence Analysis of Oligodeoxyribonucleotides Gel-Capillary Electrophoresis Analysis of Oligonucleotides Nuclear Magnetic Resonance Studies of Oligonucleotides Mass Spectrometry of Nucleotides and Oligonucleotides Extracting Thermodynamic Data from Equilibrium Melting Curves for Oligonucleotide Order-Disclosure Transitions Index

Product Details

ISBN:
9780896032521
Author:
Agrawal, Sudhir
Publisher:
Humana Press
Location:
Totowa, N.J. :
Subject:
General
Subject:
Chemistry - Organic
Subject:
Chemistry
Subject:
Oligonucleotides
Subject:
Oligonucleotides -- chemistry.
Subject:
Organic chemistry
Edition Description:
Book
Series:
Methods in Molecular Biology
Series Volume:
v. 26
Publication Date:
19931131
Binding:
TRADE PAPER
Language:
English
Illustrations:
Yes
Pages:
392
Dimensions:
229 x 152 mm 1 gr

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Protocols for Oligonucleotide Conjugates: Synthesis & Analytical Techniques New Trade Paper
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Product details 392 pages Humana Press - English 9780896032521 Reviews:
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