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Meningococcal Disease Protocols: Volume 2

by

Meningococcal Disease Protocols: Volume 2 Cover

 

Synopses & Reviews

Publisher Comments:

The development of a comprehensive vaccine against Neisseria meningitidis, the causative agent of meningococcal disease, has remained elusive because of bacterial diversity and immunologic evasion. In Meningococcal Vaccines: Methods and Protocols, Andrew Pollard and Martin Maiden have assembled an impressive collection of the latest molecular and cellular techniques for the development, evaluation, and implementation of vaccines to be used against this dreaded disease. The contributors-leading scientists, clinicians, and public health physicians-describe in detail the many approaches to vaccine design, as well as the assessment of immune response to vaccine candidates and novel vaccine formulations. They also present as a test case the recent implementation of a new meningococcal vaccine in the United Kingdom. A companion volume, Meningococcal Disease: Methods and Protocols, contains detailed methods for diagnostic microbiology, bacterial characterization, epidemiology, host-pathogen interactions, and clinical studies. Timely and comprehensive, Meningococcal Vaccines: Methods and Protocols provides the scientist, public health physician, epidemiologist, clinical microbiologist, and clinician with the essential tools to lay bare the secrets of the meningococcus and to develop, evaluate, and implement successful new meningococcal vaccines.

Book News Annotation:

Reports on the latest molecular and cellular techniques for the development, evaluation, and implementation of vaccines against Neisseria meningitidis, the causative agent of meningococcal disease. Scientists, clinicians, and public health physicians describe approaches to vaccine design and detail the assessment of immune response to vaccine candidates and novel vaccine formulations. A test case is presented on the implementation of a new vaccine in the UK. Some specific topics include recombinant proteins in vaccine development, experiences with nasal vaccines, and T-cell responses against meningococcal antigens. Pollard is affiliated with the BC Research Institute for Children's and Women's Health, Canada. Maiden is affiliated with the Wellcome Trust Center for the Epidemiology of Infectious Disease, UK.
Annotation c. Book News, Inc., Portland, OR (booknews.com)

Synopsis:

Andrew Pollard and Martin Maiden have assembled an impressive collection of the latest molecular and cellular techniques for the development, evaluation, and implementation of vaccines to be used against this dreaded disease. The contributors-leading scientists, clinicians, and public health physicians-describe in detail the many approaches to vaccine design, as well as the assessment of immune response to vaccine candidates and novel vaccine formulations. Timely and comprehensive, Meningococcal Vaccines: Methods and Protocols provides the scientist, public health physician, epidemiologist, clinical microbiologist, and clinician with the essential tools to lay bare the secrets of the meningococcus, and to develop, evaluate, and implement successful new meningococcal vaccines.

Table of Contents

Meningococcal Vaccines and Vaccine Developments Ian M. Feavers Immune Response and Host-Pathogen Interactions Andrew J. Pollard and David Goldblatt Purification of Capsular Polysaccharide Qingling Yang and Harold Jennings Protein-Polysaccharide Conjugation Zhongwu Guo and Harold Jennings N-Propionylation Zhongwu Guo and Harold Jennings Outer Membrane Protein Purification, armen Arigita, Wim Jiskoot, Matthijs R. Graaf, and Gideon F. A. Kersten Outer Membrane Protein Vesicle Vaccines for Meningococcal Disease Carl E. Frasch, Loek van Alphen, Johan Holst, Jan T. Poolman, and Einar Rosenqvist Methods for Manipulation of Transferrin-Binding Proteins Leanne M. DeWinter and Anthony B. Schryvers Methods for the Preparation and Crystallization of Fab Fragments in Complex with Peptide Antigens Derived from N. meningitidis Outer Membrane Proteins Richard F. Collins and Jeremy P. Derrick Application of Optical Biosensor Techniques to the Characterization of PorA-Antibody Binding Kinetics Janet Suker and Bambos M. Charalambous Construction of porA Mutants Peter van der Ley and Loek van Alphen Construction of LPS Mutants Peter van der Ley and Liana Steeghs Recombinant Proteins in Vaccine Development Myron Christodoulides, Keith A. Jolley, and John E. Heckels Identification of Peptides that Mimic N. meningitidis LOS Epitopes Via the Use of Combinatorial Phage-Display Libraries Paul J. Brett, Ian M. Feavers, and Bambos M. Charalambous Testing Meningococcal Vaccines for Mitogenicity and Superantigenicity Alexei A. Delvig, John H. Robinson, and Lee Wetzler Early Experiences with Nasal Vaccines against Meningococcal Disease Johan Holst and Bjørn Haneberg Animal Models for Meningococcal Disease Andrew R. Gorringe, Karen M. Reddin, Pierre Voet, and Jan T. Poolman Determination of Antibody Responses to Meningococcal Antigens by ELISA Einar Rosenqvist, Helena Käyhty, and Andrew J. Pollard Immunoblot Analysis of Sera from Patients and Vaccinees Elisabeth Wedege Serogroup B and C Serum Bactericidal Assays Ray Borrow and George M. Carlone A Modified ELISA for Measurement of High-Avidity IgG Antibodies to Meningococcal Serogroup C Polysaccharide that Correlate with Bactericidal Titers Dan M. Granoff and John J. Donnelly Whole-Blood Model Catherine A. Ison Antibody-Induced Opsonophagocytosis of Serogroup B Meningococci Measured by Flow Cytometry Terje E. Michaelsen and Audun Aase T-Cell Responses Against Meningococcal Antigens Lisbeth Meyer Næss, Fredrik Oftung, Audun Aase, Terje E. Michaelsen and Andrew J. Pollard CD4 T-Cell Epitope Mapping Alexei A. Delvig and John H. Robinson Epitope Mapping John E. Heckels and Myron Christodoulides Meningococcal Vaccine Trials Paddy Farrington and Elizabeth Miller The Introduction of Group C Conjugate Meningococcal Vaccine into the UK David M. Salisbury

Product Details

ISBN:
9780896038011
Editor:
Pollard, Andrew J.
Editor:
Maiden, Martin C. J.
Editor:
Pollard, Andrew J.
Editor:
Maiden, Martin C. J.
Author:
Pollard, Andrew J.
Author:
Maiden, Martin C. J.
Publisher:
Humana Press
Location:
Totowa, N.J.
Subject:
General
Subject:
Neurology
Subject:
Microbiology
Subject:
Pharmacology
Subject:
Therapeutic use
Subject:
Drug Therapy
Subject:
Bacterial vaccines.
Subject:
Meningitis.
Subject:
Neisseria meningitidis.
Subject:
Meningitis, Meningococcal.
Subject:
Meningococcal Vaccines
Subject:
Neurology - General
Subject:
Health and Medicine-Medical Specialties
Subject:
Infectious Diseases
Edition Description:
Book
Series:
Methods in Molecular Medicine
Series Volume:
00-48666
Publication Date:
20010631
Binding:
HARDCOVER
Language:
English
Illustrations:
Yes
Pages:
440
Dimensions:
229 x 152 mm 1 gr

Related Subjects

Health and Self-Help » Health and Medicine » Medical Specialties
Health and Self-Help » Health and Medicine » Pharmacology
Science and Mathematics » Biology » Molecular

Meningococcal Disease Protocols: Volume 2 New Hardcover
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$200.95 In Stock
Product details 440 pages Humana Press - English 9780896038011 Reviews:
"Synopsis" by , Andrew Pollard and Martin Maiden have assembled an impressive collection of the latest molecular and cellular techniques for the development, evaluation, and implementation of vaccines to be used against this dreaded disease. The contributors-leading scientists, clinicians, and public health physicians-describe in detail the many approaches to vaccine design, as well as the assessment of immune response to vaccine candidates and novel vaccine formulations. Timely and comprehensive, Meningococcal Vaccines: Methods and Protocols provides the scientist, public health physician, epidemiologist, clinical microbiologist, and clinician with the essential tools to lay bare the secrets of the meningococcus, and to develop, evaluate, and implement successful new meningococcal vaccines.
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