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Practical Approach Series #251: Molecular Epidemiology

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Practical Approach Series #251: Molecular Epidemiology Cover

 

Synopses & Reviews

Publisher Comments:

Provides a broad overview of the diverse approaches encompassed by the emerging discipline of molecular epidemiology. Concepts and methods at the forefront of infectious disease studies are discussed along with recent advances in studying host genetics, methods for the detection of mutations and polymorphisms, the relationship between pathologies and immune system genetics, and the use of DNA sequence information to garner insights into the evolution of infectious pathogens. The evolution and function of the immune system and a synopsis of general epidemiological design and analysis are included.

Book News Annotation:

Seventeen specialists (16 Americans and one Italian) contribute eight chapters to this volume exploring the wide range of approaches being used in the field of molecular epidemiology. Coverage includes cutting-edge concepts and methods in the study of infectious diseases, with a synopsis of general epidemiologic design and analysis, and current techniques for molecular typing of microbial pathogens; recent advances in studying host genetics, including methods for the detection of mutations and polymorphisms, identification of linkage among alleles of genes on a given chromosome, and the use of DNA pooling to increase efficiency in association studies of genetically complex traits; the relationship between pathologies and immune system genetics; the use of DNA sequence information to gain insights into the evolution of infectious pathogens; and the evolution and function of the immune system.
Annotation c. Book News, Inc., Portland, OR (booknews.com)

Table of Contents

List of Protocols

Abbreviations

Introduction to molecular epidemiology, Charles S. Rabkin and Nathaniel Rothman

References

1. Epidemiological methods for studies of genetic factors that influence infectious diseases, Eric A. Engels and Thomas R. O'Brien

2. Molecular differentiation of bacterial strains, Eric W. Brown

3. Detection and quantification of heterogeneous viral targets: HIV as a model, Shirley Kwok

4. Mutation detection by single-stranded conformation polymorphism and denaturing high performance liquid chromatography, Michael Dean, Bernard Gerrard, and Rando Allikmets

5. DNA pooling methods for association mapping of complex disease loci, Lisa F. Barcellos, Soren Germer, and William Klitz

6. Single-sperm typing: a rapid alternative to family-based linkage analysis, Michael Cullen and Mary Carrington

7. PCR-based methods of HLA typing, Henry A. Erlich and Elizabeth A. Trachtenberg

8. Evolutionary analysis of molecular sequence data, Austin L. Hughes, Jack da Silva, and Federica Verra

List of suppliers

Index

Product Details

ISBN:
9780199638109
Author:
Carrington, Mary
Author:
Hoelzel, Rus
Author:
Hoelzel, A. Rus
Author:
Hoelzel, A. R.
Author:
null, Mary
Author:
null, A. Rus
Publisher:
Oxford University Press, USA
Location:
Oxford
Subject:
Genetics
Subject:
Epidemiology
Subject:
Biostatistics
Subject:
Laboratory Medicine
Subject:
Molecular epidemiology.
Subject:
ndocrinology & Metabolism
Subject:
Medicine | Epidemiology
Subject:
Medicine | Epidemiology and Biostatistics
Subject:
Medicine | Epidemiology & Biostatistics
Subject:
Health and Medicine-Medical Specialties
Edition Description:
Includes bibliographical references and index.
Series:
Practical approach series ;
Series Volume:
32251
Publication Date:
20020131
Binding:
TRADE PAPER
Grade Level:
College/higher education:
Language:
English
Illustrations:
24 line illus and 7 halftones
Pages:
264
Dimensions:
9.600 x 7.400 in 1.310 lb

Related Subjects

Business » Accounting and Finance
Health and Self-Help » Health and Medicine » Medical Specialties
History and Social Science » Law » General
Science and Mathematics » Biology » Molecular

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