Synopses & Reviews
Synopsis
Excerpt from A Study of the Hemolytic Antibody-Antigen Combination: Dissertation; Submitted to the Director of the School of Hygiene and Public Health in Conformity With the Requirements for the Degree of Doctor of Science in Hygiene
According to Ehrlich (l), a formed antigen, such as a red cell or bacterium, has a definite number of com bining groups which have an affinity for the antibody. When the antigen is placed in contact with its antibody, a reaction ensues, which progresses until all these bonds are satisfied or until all the antibodies have entered into the combination. It follows from this that when all the combining affinities of the antigen are satisfied, no more antibodies can enter into the reaction regardless of the number that still remain free in the supernatant fluid. This theory implies chemical affinities and a combination according to the respective valencies of the reacting substances.
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