This book provides an integrated perspective on the recent advances in the development of effective biological systems using molecular biological techniques for biochemical production and analysis.
Preface
1. Biological Systems Engineering: An Overview, Mark R. Marten, Tai Hyun Park, and Teruyuki Nagamune
Microbial and Enzymatic Systems
2. Metabolic Systems Engineering Approach for Efficient Microbial Fermentation and Future Perspectives
3. Engineering of Escherichia coli Central Metabolic Pathways for the Production of Succinic Acid, S. Y. Lee and S. H. Hong
4. Metabolic Control Analysis in Glutamate Synthetic Pathway: Experimental Sensitivity Analysis at a Key Branch Point, Hiroshi Shimizu, Hisaya Tanaka, Akinori Nakato, Keisuke Nagahisa, and Suteaki Shioya
5. Biological Production of Xylitol by Candida tropicalis and Recombinant Saccharomyces cerevisiae Containing Xylose Reductase Gene, Kwan-Hoon Moon, Woo-Jong Lee, Jay-Han Kim, Jin-Ho Choi, Yeon-Woo Ryu, and Jin-Ho Seo
6. Plate and Disk Bioreactors for Making Bacterial Cellulose, Peter Gostomski, Henry Bungay, and Richard Mormino
7. The Effect of the Dissolved Oxygen Concentration on the Production of Lignin Peroxidase and Manganese Peroxidase by Phanerochaete chrysosporium, Sue Hyung Choi, Man Bock Gu, and Seung-Hyeon Moon
8. Development of Effective Immobilization Method Using Modified Glutaraldehyde for GL-7-ACA Acylase, Seung Won Park, Sang Yong Choi, Koo Hun Chung, Suk In Hong, and Seung Wook Kim
9. Production of Laccase by Membrane-Surface Liquid Culture with Nonwoven Fabric of Coriolus versicolor, Kazuhiro Hoshino, Mami Yuzuriha, Shoichi Morohashi, Shigehiro Kagaya, and Masayuki Taniguchi
10. Hydrolysis of Paper Sludge Using Mixed Cellulase System:Enzymtic Hydrolysis of Paper Sludge, Sang-Mok Lee, ianqiang Lin, and Yoon-Mo Koo
Animal Cell Systems
11. Antigen-Mediated Genetically Modified Cell Amplification, Masahiro Kawahara, Hiroshi Ueda, Kouhei Tsumoto, Izumi Kumagai, Walt Mahoney, and Teruyuki Nagamune
12. Beneficial Effects of Silkworm Hemolymph on the Cultivation of Insect Cell-Baculovirus System, Tai Hyun Park, Won Jong Rhee, and Eun Jeong Kim
13. Apoptotic Signal Transduction by Cadmium Ion and Detoxification by Plant Peptides, Masahiro Takagi, Hiroyuki Satofuka, and Tadayuki Imanaka
14. Chemotherapy with Hybrid Liposomes Composed of Dimyristoylphosphatidylcholine and Polyoxyethylenealkyl Ether without Drugs, Ryuichi Ueoka, Yoko Matsumoto, Hideaki Ichihara, and Tetsushi Kiyokawa
15. Apoptosis Inhibiting Genes and Caspase Inhibitors Improved Mammalian Cell Survival and Enhanced, Protein Production
16. Presence of Catalytic Activity of the Antibody Light Chain Raised against Complementarity Determining Region Peptide of Super Catalytic Antibody, Y. Zhou, E. Hifumi, H. Kondo, and T. Uda
Combinatorial Bioengineering and Analytical Methods
17. Synthesis and Analysis of Peptide Ligand for Biosensor Application Using Combinatorial Chemistry: Screening and Characterization of 2,3,7-trichlorodibenzo-p-dioxin-Binding Peptide, Yasutaka Morita, Yuji Murakami, Kenji Yokoyama, and Eiichi Tamiya0
18. Construction of a Combinatorial Protein Library Displayed on Yeast Cell Surface and Its Application to Molecular Breeding, Wen Zou, Mitsuyoshi Ueda, and Atsuo Tanaka
19. Construction of Surface-Engineered Arming Yeasts with Fluorescent Protein Sensors in Response to Environmental Changes, Seiji Shibasaki, Mitsuyoshi Ueda, and Atsuo Tanaka
20. Sensor Peptides Based on Fluorescence Resonance Energy Transfer, Kenji Yokoyama, Masayuki Matsumoto, Hideo Ishikawa, Yasutaka Morita, and Eiichi Tamiya
21. Immobilized Fluorescent Liposome Column for Bioanalysis and Signal Amplification, Xue-Ying Liu, Chikashi Nakamura, and Jun Miyake
22. Analysis and Optimization of Biopanning Process
of Phage Display Libraries Yoshio Katakura, Guoqiang Zhuang, Satoshi Uchida, Tetsuo Furuta, Takeshi Omasa, Michimasa Kishimoto, and Ken-ichi Suga
23. Open Sandwich Selection: Selection of Human Antibody Fragments Using the Mechanism of Fv Fragment Stabilization in the Presence of Antigen, Kouhei Tsumoto, Hideki Watanabe, and Izumi Kumagai
Indexes
Author Index
Subject Index