Synopses & Reviews
Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function.
Synopsis
With BAI being one of the most common complications associated with implantation of any biomaterial, this vital book features contributions from leaders in the field who address this critical problem in applying biomaterials research to clinical practice.
Synopsis
Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function. These infections usually involve bacterial colonization and biofilm formation on the biomaterial itself, rendering the infection impervious to antimicrobials and host defenses. In addition, it is becoming increasingly clear that infection of the surrounding tissues also plays an important role in BAI, and that the infection may be influenced by the composition and design of the implanted biomaterial. In this book, worldwide leaders in the field address this critical problem in the translation of biomaterials research into clinical practice. The book begins with an emphasis on the latest research in the pathogenesis of BAI from microbiological, immunological, and materials science perspectives. The current state of the art in antimicrobial activation of biomaterials through surface modification and the incorporation of antimicrobial agents is then discussed. In the concluding chapters, successful translation of a selection of antimicrobial technologies from preclinical research into clinical use is described alongside a discussion of the utility of these devices and perspectives for future development. This book is essential reading for researchers and clinicians who are interested in understanding the fundamentals of BAI, the latest in antimicrobial materials research, and the state of the art in clinically available antimicrobial containing medical devices.
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Table of Contents
PART 1. The Pathogenesis of Medical Device associated Infection Chapter 1. Biomaterial associated infection: a perspective from the clinic.
Chapter 2. Staphylococcus epidermidis in biomaterial associated infection
Chapter 3. Staphylococcus aureus in biomaterial associated infection
Chapter 4. New emerging pathogens in biomaterial associated infection
Chapter 5. Bridging the gap between in vitro and in vivo testing for Biomaterial associated infection.
Chapter 6. Biomaterial-dependent characteristics of the