Synopses & Reviews
In past decades, the area of bioinformatics has proved to be both dynamic and vital, producing a wide spectrum of novel approaches and assuming an increasingly important role in modern bio-technological development. In Biomedical Informatics, expert researchers explore cutting-edge new advances in the field, providing an overview of novel cyberinfrastructures which are currently under development in various bio-medical centers across the world. Chapters demonstrate various architectures for large-scale collaboration, offer modern approaches currently used in various areas of bioinformatics, and highlight the software challenges associated with large-scale biomedical informatics. Composed in the highly successful Methods in Molecular Biology™ series format, chapters include a brief introduction, detailed methods, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Wide-ranging and innovative, Biomedical Informatics is an essential manual for newcomers to this area, as well as an invaluable addition to the laboratories and offices of the most practiced researchers.
In this text, expert researchers explore cutting-edge advances in the field of bioinformatics, providing an overview of novel cyberinfrastructures which are currently under development in various biomedical centers across the world.
Table of Contents
Table of Contents Table of Contents Preface Contributors 1. Management of Information in Distributed Biomedical Collaboratories David B. Keator 2. Enabling Public Data Sharing: Encouraging Scientific Discovery and Education Christine Fennema-Notestine 3. Mediator Infrastructure for Information Integration And Semantic Data Integration Environment for Biomedical Research Jeffrey S. Grethe, Edward Ross, David Little, Brian Sanders, Amarnath Gupta, Vadim Astakhov 4. System Biology of Gene Regulation Michael Baitaluk 5. Current computational methods for prioritizing candidate regulatory polymorphisms Stephen Montgomery 6. Methods of information geometry in computational system biology (Consistency between Chemical and Biological Evolution) Vadim Astakhov 7. Protein Structure Prediction based on Sequence Similarity Lukasz Jaroszewski 8. Applications of Bioinformatics to Protein Structures - How Protein Structure and Bioinformatics Overlap Gye Won Han, Chris Rife, Michael R. Sawaya 9. Knowledge Discovery via Machine Learning for Neuro-degenerative Disease Researchers I. Burak Özyurt, Gregory G. Brown 10. Brain Model of Text Animation as a Data Mining Strategy Tamara Astakhova, Vadim Astakhov 11. Processes Parallelization Using "Grid Wizard Enterprise" Marco Ruiz 12. Single Sign-On in a Grid Portal Ramil V. Manansala