Synopses & Reviews
This book discusses the ecology of viruses with an emphasis on the emergence of devastating hemorrhagic diseases, and a review of the molecular and cellular basis of the pathogenesis of several viral diseases. The volume provides an introduction to the mathematical analysis of recurrent epidemic viral diseases and examines the neurological and psychological diseases in relation to the pathological mechanisms underlying prion disease. Chapters explore new viral threats including HIV, bunyaviruses, morbilliviruses and caliciviruses.
"I wish every politician, ideologue, and guru in the world would read this book because the likeliest catastrophes in humanity's immediate future are not political, ideological, or religious, but viral...The articles are not sensationalistic...but calm and deeply informed. They are excellent sources for experts...This is an informed and dispassionate study...It is an excellent brief for those who worry more about public health than ICBMs." Quarterly Review of Biology
Presents the latest discussions of the ecology of viruses and reviews the underlying mechanisms by which viruses cause disease.
About the Author
Geoffrey Smith is a Wellcome Trust Principal Research Fellow at the Wright-Fleming Institute, Imperial College of Science, Technology and Medicine, UK.Will Irving is a Reader in Virology in the Department of Microbiology at the University of Nottingham, UK.John McCauley is a researcher in the Division of Molecular Biology at the Institute of Animal Health, Compton. UK.Dave Rowlands is Professor of Molecular Virology in the Division of Microbiology at the University of Leeds, UK.
Table of Contents
Preface; 1. The viruses in our past, the viruses in our future C. J. Peters; 2. Dynamics and epidemiological impact of microparasites B. T. Grenfell; 3. The continuing threat of bunyaviruses and hantaviruses R. M. Elliott; 4. Calicivirus, myxoma virus and the wild rabbit in Australia: a tale of three invasions B. J. Richardson; 5. Potential of influenza A viruses to cause pandemics A. J. Hay; 6. The hepatitis viruses as emerging agents of infectious diseases S. M. Lemon; 7. The emergence of human immunodeficiency viruses and AIDS R. A. Weiss and H. A. Weiss; 8. Morbilliviruses: dangers old and new T. Barrett; 9. Structure-function analysis of prion protein C. Weissmann, D. Shmerling, D. Rossi, A. Cozzio, I. Hegyi, M. Fischer, R. Leimeroth and E. Flechsig; 10. Endogenous retroviruses and xenotransplantation J. P. Stoye; 11. Gammaherpesviral infections and neoplasia in immunocompromised populations C. Boshoff; 12. Structure and function of the proteins of Marburg and Ebola viruses H.-D. Klenk, H. Feldmann, V. E. Volchkov, V. A. Volchkova and W. Weissenhorn; 13. Epidemic dengue/dengue haemorrhagic fever as a public health problem 1st century D. J. Gubler; 14. Borna disease virus - a threat for human mental health? L. Bode and H. Ludwig; 15. Antiviral drug development and the impact of drug resistance G. Darby; Index.