Synopses & Reviews
The prevalence of hypertension is almost three times as high as diabetes mellitus, and both conditions are major risk factors for stroke, ischemic heart disease, arrhythmias, and heart failure. Although the exact prevalence of hypertension related to hormonal derangements, also named endocrine hypertension, is not known (but estimated to affect less than 15% of all hypertensive patients), recent scientific discoveries have elucidated and broadened our understanding of pathophysiologic mechanisms leading to hypertension. For many conditions related to endocrine hypertension (for instance, adrenal tumors secreting aldosterone or cortisol in excess), identifying the cause may even lead to curative therapy (normotension), if undertaken in timely manner. The challenge remains when to consider endocrine hypertension and this essential guide assists in that endeavor.Divided into three sections, each covering an endocrine organ, Endocrine Hypertension: Underlying Mechanisms and Therapy begins with the adrenal gland, which harbors well-known causes of endocrine hypertension, and is followed by the pituitary, thyroid and parathyroid glands, with conditions less known to be associated with endocrine hypertension. The third part is devoted to topics that are still controversial in their relationship to endocrine hypertension such as the metabolic syndrome, including insulin resistance, testosterone and growth hormone deficiency, and vitamin D deficiency. An invaluable reference for all clinicians and scientists concerned with hypertension, Endocrine Hypertension: Underlying Mechanisms and Therapy synthesizes the literature and provides a more thorough understanding of the causes and consequences of the problem.
Synopsis
Endocrine Hypertension provides a comprehensive overview of this disorder, discussing when to assign an endocrine cause to the many conditions that present in the hypertensive patient. Covers adrenal hypertension, and many potential nonadrenal causes.
Table of Contents
Part I: Adrenal Hypertension Primary Aldosteronism: Progress in Diagnosis, Therapy, and Genetics Paolo Mulatero, Tracy Ann Williams, Silvia Monticone, Andrea Viola, Davide Tizzani, Valentina Crudo, Jacopo Burrello, Franco Veglio Syndromes of Mineralocorticoid ExcessEugen Melcescu, MD, and Christian A. Koch, MD, PhD, Hypertension in Patients with Cushing's Syndrome: Vitaly Kantorovich, Christian A. Koch, George P. Chrousos Primary Generalized Familial and Sporadic Glucocorticoid Resistance (Chrousos syndrome) and HypersensitivityEvangelia Charmandari, Tomoshige Kino, and George P. Chrousos