Synopses & Reviews
This is the first comprehensive text on the methodological issues in epidemiologic research on infectious diseases. It will be an invaluable resource both to students of epidemiology and to established researchers. The authors address such questions as: What needs to be considered when enrolling participants in a study of sexually transmitted diseases? What are common sources of measurement error in population-based studies of respiratory infections? What are some sources of existing data for epidemiologic studies of infectious diseases? Answers to these and many other related questions can be found in this well-organized, comprehensive and authoritative volume - the first to thoroughly address the methodologic issues in conducting epidimiologic research on infectious diseases. The book will be an ideal complement to texts on general epidemiology and infectious disease. An introductory section will make it accessible to a wide variety of disciplines by providing an overview of topics that are foundational to understanding infectious disease epidemiology, such as the immunology of infections, the biology of infectious diseases, and concepts of causation, transmission, and dynamics. The rest of the book is structured around sections on data sources and measurement; methods by transmission type; outbreak investigation and evaluation research; and special topics such as HIV/AIDS research, infections in the elderly, and research collaborations in developing countries.
Table of Contents
PART I: Foundations 1. Biological Basis of Infectious Disease Epidemiology, David J. Weber and William A. Rutala
2. Immune Response and Methods for Detection of Infectious Diseases, Amy L. Peace-Brewer, Kimberly L. Kane, and James D. Folds
3. Theories of Causation, Dana Loomis and Steve Wing
4. Concepts of Transmission and Dynamics, M. Elizabeth Halloran
5. Overview of Study Design, M. Elizabeth Halloran
PART II: Data Sources and Measurement
6. Sources of Data, D. Peter Drotman and Marc A. Strassburg
7. Disease Surveillance, Terence L. Chorba
8. Microbial Molecular Techniques, Loreen A. Herwaldt, Michael A. Pfaller, and Stefan Weber
9. Evaluation of Diagnostic Tests, Robert H. Fletcher and Scott B. Halstead
PART III: Methods by Transmission Type
10. Respiratory Transmission, Jack M. Gwaltney, Jr. and J. Owen Hendley
11. Fecal-Oral Transmission, Karin E. Byers, Richard L. Guerrant, and Barry M. Farr
12. Vector-borne Transmission, Frank J. Sorvillo, Amy C. Morrison, O. G. W. Berlin
13. Sexual Transmission, James C. Thomas and Sara Stratton
PART IV: Outbreak Investigation and Evaluation Research
14. Investigation of Outbreaks, David J. Weber, L. Bernardo Menajovsky, and Richard Wenzel
15. Clinical Trials, Harry A. Guess and Gary B. Calandra
16. Community Intervention Studies, James C. Thomas
17. Evaluation of Immunization Programs, Robert T. Chen and Walter A. Orenstein
PART V: Research in Special Populations or Settings
18. Research in Out-of-Home Child Care, Ralph L. Cordell, Larry K. Pickering, and M. Louise Lawson
19. Infections Among the Elderly, Laura C. Hanson
20. HIV/AIDS Research, Sten H. Vermund, et al.
21. Research Collaborations in Developing Countries, Maria J. Wawer
Glossary Index