Synopses & Reviews
Synopsis
This is the second edition of the comprehensive, concise summary of apoptosis research. It covers the major concepts, molecular architecture, the biochemical pathways, and pathophysiological significance of apoptosis. This book provides a guideline of standard biochemical and cell biologic approaches to apoptosis bench work with an emphasis on translational clinical applications for immune disorders, cancer research, ischemia, and neuronal degeneration. Since the original publication in 2003, the apoptosis field has expanded rapidly - chapters not only need to be revised and expanded, but there is a need for all new chapters covering exciting advances in bioinformatics, systems biology, oxidative stress, etc.
Synopsis
Essentials of Apoptosis (2nd edition) Table of Contents Preface (2nd edition) Preface (1st edition) Contributors Part I. Molecules and Pathways of Apoptosis Chapter 1. Caspases: Activation, Regulation and Function Stefan J. Riedl and Fiona L. Scott Chapter 2. Bcl-2 Family Proteins Wenxing Ding and Xiao-Ming Yin Chapter 3. The Mammalian IAPs: Multi-faceted Inhibitors of Apoptosis Eric C. LaCasse, Herman H. Cheung, Allison M. Hunter, Stephanie Plenchette, Douglas J. Mahoney and Robert G. Korneluk Chapter 4. Structure Biology of Programmed Cell Death Yigong Shi Chapter 5. The Death Receptor Pathway Maria Eugenia Guicciardi and Gregory J. Gores Chapter 6. The Mitochondrial Pathway: Focus on Shape Changes Silvia Campello and Luca Scorrano Chapter 7. The Endoplasm Reticulum Pathway Michael W. Harr and Clark W. Distelhorst Chapter 8. Reactive Oxygen Species in Cell Fate Decisions Han-Ming Shen and Shazib Pervaiz Chapter 9. The Integration of Metabolism and Cell Death Jonathan L. Coloff, Yuxing Zhao and Jeffrey C. Rathmell Chapter 10. Transcriptional Regulation of Apoptosis Crissy Dudgeon, Wei Qiu, Quanhong Sun, Lin Zhang and Jian Yu Chapter 11. Clearance of Apoptotic cells --Mechanisms and Consequences Carylin J. Marek and Lars-Peter Erwig Chapter 12. Systems Biology Approach to the Study of Apoptosis Heinrich Huber, Eric Bullinger and Markus Rehm Part II: Apoptosis in Model Organisms Chapter 13. Programmed Cell Death in Plants: Apoptotic but not Quite Naohide Watanabe and Eric Lam Chapter 14. Tracing the Roots of Death: Apoptosis in Saccharomyces cerevisiae Didac Carmona-Gutierrez and Frank Madeo Chapter 15. Programmed Cell Death in C. elegans. Monica Darland-Ransom, Yi-Chun Wu and Ding Xue Chapter 16. Cell Death in Drosophila. Dianne C. Purves, Jessica P. Monserrate and Carrie Baker Brachmann Part III. Apoptosis in Mammalian Physiology and Pathogenesis Chapter 17. Cell Death: Defining and Misshaping Mammalian Embryos Zahra Zakeri and Richard Lockshin Chapter 18. Matters of Life and Death in the Immune System Christopher Dillon and Douglas R. Green Chapter 19.Cell Death in the Hematopoietic System Emma C. Josefsson and Benjamin T. Kile Chapter 20 Cell Death in Acute Neuronal Injury R. Anne Stetler, Armando P. Signore and Jun Chen Chapter 21. Apoptosis in Neurodegenerative Diseases Qiuli Liang and Jianhua Zhang Chapter 22. Apoptosis in Cardiovascular Pathogenesis Hamid el Azzouzi; Meriem Bourajjaj; Paula A. da Costa Martins and Leon J. De Windt Chapter 23. Apoptosis in Lung Injury and Disease Stefan W. Ryter, Hong Pyo Kim, and Augustine M. K. Choi Chapter 24. Apoptosis in the Liver Injury and Liver Diseases Yosuke Osawa, Ekihiro Seki, and David A Brenner Chapter 25. Apoptosis in Kidney Injur