Synopses & Reviews
Synopsis
1. Epidemiologic Evidence for the Obesity-Endometrial Cancer Relationship.- 2. Epidemiologic Relationship Between Obesity and Ovarian Cancer.- 3. Public Knowledge of Obesity and Gynecologic Cancer Risk.- 4. Role of Estrogen and Progesterone in Obesity Associated Gynecologic Cancers.- 5. Obesity and Endometrial Cancer Precursors.- 6. Obesity, Adipokines, and Gynecologic Cancer.- 7. Adipose Derived Stromal Cells in Gynecologic Cancers.- 8. Obesity and Endometrial Cancer: Mouse Models for Preclinical Prevention Studies.- 9. Lifestyle Interventions to Reduce the Risk of Obesity-Associated Gynecologic Malignancies: A Focus on Endometrial Cancer.- 10. Hormonal and Metabolic Strategies to Overcome Insulin Resistance and Prevent Endometrial Cancer.- 11. Management of Endometrial Cancer Precursors in Obese Women.- 12. Exercise and Lifestyle Interventions in Gynecologic Cancer Survivors.- 13. Physical Activity as a Risk Factor for Ovarian Cancer.- 14. Impact of Obesity on Surgical Approaches to Gynecologic Malignancies.- 15. Obesity, Fertility Preservation and Gynecologic Cancers.- 16. Metformin as Adjuvant Therapy in Ovarian and Endometrial Cancers.
Synopsis
Examines the relation of obesity to endometrial cancer and to ovarian cancer while providing insight into public understanding of the importance of obesity as a risk factor for gynecologic malignancies
Describes major aspects of biology relating obesity to gynecologic cancer including hormonal status, adipokines, adipose stromal cells and in particular, use of model systems to study the impact of obesity in gynecologic malignancies
Discusses the multiple prevention strategies including hormone and lifestyle interventions, extending even to bariatric surgery, along with detailed effects of the impact of obesity on treatment strategies and approach to unique outcomes