Synopses & Reviews
This book is about the vascular endothelium, the layer of cells that lines the inner side of all blood vessel walls. It describes the role of the endothelium in inflammation and immunity with particular regard for autoimmune kidney, rheumatic and neurological disease, as well as in transplantation. The importance of this book, and its main difference from others, is that it seeks to link basic scientific knowledge of the role of the endothelium in inflammation and immunity with what may happen in disease states.
Review
"This is a stimulating monograph...recommended for readers interested in the endothelium and its rapid ascendance to the status of an immunologic organ." John A. Robinson, Doody's Health Sciences Book Review Journal
Synopsis
An 1995 look at the functioning of the vascular endothelium, and the diseases that arise as a result of inflammation and immunological responses.
Table of Contents
1. New concepts of mechanisms in autoimmunity; 2. Regulation of endothelial cell function by cytokines; 3. Interactions between granulocytes and endothelium; 4. The regulation of lymphocyte migration by vascular endothelium and its role in the immune response; 5. The role of the vascular endothelium in immunologically-mediated neurological diseases; 6. The role of the endothelium in systemic lupus erythematosus and Sjögren's syndrome; 7. The role of the endothelium in rheumatoid arthritis and scleroderma; 8. The role of the endothelium in systemic vasculitis; 9. Endothelial involvement in childhood Kawasaki disease; 10. The role of the endothelium in thrombotic thrombocytopaenic purpura and haemolytic uraemic sydrome; 11. The immunological role of the endothelium in organ transplantation; Index.