Synopses & Reviews
The discovery that inositol lipids are integral in cellular signaling mechanisms has been one of the most exciting breakthroughs in recent years. As secondary messengers in a wide variety of tissues and involved processes as diverse as rapid contraction of skeletal muscle, insulin secretion, and the slow activation of cell proliferation in cancer cells, their impact on biochemistry is akin to that of cyclic AMP two decades ago. Drawing together the many strands of research on inositol lipid-mediated signalling and containing contributions by leading authorities in their fields, Inositol Lipids in Cell Signalling is essential for any involved biochemist, cell biologist, or pharmacologist.
Table of Contents
on.
The Pituitary Gland and its Constituent Cells.
Phosphoinositide Metabolism and Excitation-Contraction Coupling in Smooth, Cardiac, and Skeletal Muscle.
Generation, Metabolism and Function of Inositol Phosphates during Nutrient and Neurotransmitter Induced Insulin Secretion.
Inositol Lipid Signalling in Cell Growth and Development.
Inositol Phospholipid Involvement in T and B Lymphocyte Proliferation.
Phosphoinositide Second Messengers in Eggs and Oocytes.
Inositol Lipids in Growth Factor Action.
The Role of Oncogene and Proto-Oncogene Products in Signal Transduction.
List of Contributors.
Index.