Synopses & Reviews
The massive research effort known as the Human Genome Project is an attempt to record the sequence of the three trillion nucleotides that make up the human genome and to identify individual genes within this sequence. The description and classification of sequences is heavily dependent on mathematical and statistical models. This short textbook presents a brief description of several ways in which mathematics and statistics are being used in genome analysis and sequencing.
Review
"Mathematics of Genome Analysis is a suitable textbook for a mathematics course aimed at raising awareness of the challenges that are posed by computational biology. It is also good first reading for mathematics students and professionals who want to get an idea of the exciting mathematical problems in the analysis of biological sequences." Phyics Today"This is a lovely, short textbook on selective mathematical models in genomic DNA sequence analysis.... its style is unique..." The Quarterly Review of Biology
Synopsis
Presents a brief description of several ways in which mathematics and statistics are being used in genome analysis and sequencing.
Table of Contents
Preface; 1. Decomposing DNA; 2. Recomposing DNA; 3. Sequence statistics; 4. Sequence comparison; 5. Spatial structure and dynamics of DNA; Bibliography; Index.