Synopses & Reviews
The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to successful drug delivery. Therefore, ocular transporters and receptors are important targets for drug delivery. Significant advancements have been made in the field of ocular transport research. In this book, chapter authors describe the cutting edge research being carried out and focus specifically on the anatomy and physiology of the eye, biology of ocular transporters and receptors, techniques in characterization of transporters and receptors, transporters and receptors in the anterior and posterior segment in the eye, the role of ocular transporters and receptors in drug delivery, and transporter-metabolism interplay in the eye.
About the Author
Dr. Ashim K. Mitra is currently Vice Provost for Interdisciplinary Research in the University of Missouri at Kansas City. He is also the University of Missouri Curators' Professor of Pharmacy, Chairman of the Division of Pharmaceutical Sciences, and Co-Director of the School of Medicine's Vision Research Center.
Table of Contents
Eye: anatomy, physiology and barriers to drug delivery; Biology of ocular transporters: efflux and influx transporters in the eye; Characterization of ocular transporters; Transporters and receptors in the anterior segment of the eye; Transporters and receptors in the posterior segment of the eye; Transporters in drug discovery and delivery: a new paradigm in ocular drug design; Transporter-metabolism interplay in the eye