Synopses & Reviews
An excellent introduction for chemistry, biology, and premed majors, ORGANIC CHEMISTRY, Fifth Edition, delivers cutting-edge coverage that is packed with student-friendly features. Offering a clear presentation, the book offsets reaction mechanisms in a stepwise fashion and emphasizes similarities between related mechanisms. And, for the first time, it introduces organic chemistry of sulfur and phosphorus. ORGANIC CHEMISTRY, Fifth Edition, is renowned for its unified mechanistic themes, emphasis on biological examples, use of applied problems from the pharmaceutical field, and unrivaled full-color visuals. The new fifth edition features increased coverage of bioorganic chemistry, expanded in-text learning tools, and even stronger media integration--including ORGANIC OWL, its powerful Web-based homework system. Numerous resources help ensure student success in the course, including a running margin glossary, an in-text study guide, and more in-chapter examples than any text on the market. The text also emphasizes how-to skills throughout and is packed with challenging synthesis problems as well as medicinal chemistry problems.
This book provides an exciting introduction to organic chemistry for students majoring in chemistry and in related disciplines, especially the health and biological sciences. In this Fourth Edition, Brown, Foote, and Iverson build on the text's highly-praised hallmarks of unifying mechanistic themes, focusing on problem-solving, using applied problems from the pharmaceutical field, and making innovative use of color and emphasis on visualization. The new edition features increased coverage of mechanisms, more examples of bio-organic chemistry especially relevant to pre-medical students, new in-text learning aids including "How To" boxes, and state-of-the-art text/media integration with the Organic ChemistryNow™ Website.
About the Author
William H. Brown is Emeritus Professor of Chemistry at Beloit College, where he has twice been named Teacher of the Year. His teaching responsibilities include organic chemistry, advanced organic chemistry, and, more recently, special topics in pharmacology and drug synthesis. He received his Ph.D. from Columbia University under the direction of Gilbert Stork and did postdoctoral work at California Institute of Technology and the University of Arizona.Christopher S. Foote received his B.S. in 1957 from Yale University and his Ph.D. in 1962 from Harvard University. His scholarly credits include Sloan Fellow 1965-1967; Guggenheim Fellow 1967-1968; ACS Baekland Award, 1975; ACS Cope Scholar, 1994; Southern California Section ACS Tolman Medal, 1996; President, American Society for Photobiology, 1988-1989; and Senior Editor, ACCOUNTS OF CHEMICAL RESEARCH. He was Professor of Chemistry at UCLA.Brent L. Iverson received his Ph.D. from Stanford University in 1982 and currently teaches at University of Texas, Austin. He is a distinguished teacher and respected researcher. Iverson's research group has developed methods for recombinant antibody or enzyme cloning and has directed its evolution. In collaboration with the Georgiou group, he pioneered a novel E. coli surface expression/FACS selection technology that has allowed the group to enhance antibody affinity.Eric Anslyn, the Norman Hackerman Professor of Chemistry at The University of Texas at Austin, joins as a new co-author. Highly respected in organic chemistry, he earned his Ph.D. from the California Institute of Technology and has won numerous teaching awards. Anslyn's research focuses on the cutting-edge area of bioorganic chemistry.
Table of Contents
1. Covalent Bonding and Shapes of Molecules. 2. Alkanes and Cycloalkanes. 3. Stereochemistry and Chirality. 4. Acids and Bases. 5. Alkenes. 6. Reactions of Alkenes. Summary of Stereochemical Terms. 7. Alkynes. 8. Haloalkanes, Halogenation, and Radical Reactions. 9. Nucleophilic Substitution and ß-Elimination. 10. Alcohols. 11. Ethers, Sulfides, and Epoxides. 12. Infrared Spectroscopy. 13. Nuclear Magnetic Resonance Spectroscopy. 14. Mass Spectrometry. 15. Organometallic Compounds. 16. Aldehydes and Ketones. 17. Carboxylic Acids. 18. Functional Derivatives of Carboxylic Acids. 19. Enolate Anions and Enamines. 20. Conjugated Systems. 21. Benzene and the Concept of Aromaticity. 22. Reactions of Benzene and its Derivatives. 23. Amines. 24. Carbon-Carbon Bond Formation and Synthesis. 25. Carbohydrates. 26. Lipids. 27. Amino Acids and Proteins. 28. Nucleic Acids. 29. Organic Polymer Chemistry. Appendices: 1. Thermodynamics and the Equilibrium Constant. 2. Major Classes of Organic Acids. 3. Bond Dissociation Enthalpies. 4. Characteristic ¹H-NMR Chemical Shifts. 5. Characteristic ¹³C Chemical Shifts. 6. Characteristic IR Absorption Frequencies. 7. Understanding Electrostatic Potential Maps. Glossary. Index.