Synopses & Reviews
Introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance.
Synopsis
This book introduces methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways and discusses the design and analysis of systems models. All concepts are derived from first principles, the text is illustrated with graphs and examples, and two detailed case studies are presented.
Synopsis
This book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. All concepts are derived from first principles, and the text is illustrated with graphs and examples throughout. Other special features include introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.
Table of Contents
Preface; 1. Target: a useful model; 2. Methods of biochemical systems theory; 3. A model of citric acid production in the mold Aspergillus niger; 4. Optimization methods; 5. Optimization of biochemical systems; 6. Optimization of citric acid production in Aspergillus niger; 7. Maximization of ethanol and carbohydrate production in Saccharomyces cerevisiae; 8. Conclusions; Author index; Subject index.