Synopses & Reviews
The field of DNA repair is vast and advancing rapidly. Silencing, Heterochromatin and DNA Double Strand Break Repair probes the relationship of DNA break repair and silent heterochromatin, using budding yeast as a model. The primary research presented in this book represents some of the most important work in this new field of inquiry.
Table of Contents
Dedication. Foreword. Acknowledgements. 1. Introduction to silencing, heterochromatin, and DNA break repair. 2. Identification and characterization of high-copy antagonists of silencing in Saccharomyces cerevisiae. 3. MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks. 4. The antisilencing gene ASF1 encodes a DNA repair protein required for nonhomologous end-joining. 5. Summary and Conclusions. Appendices. References. Index.