Synopses & Reviews
Silk has been used for centuries in medicine as sutures. The unique mechanical and chemical properties of this material and the ability to genetically tailor the protein have meant that silk is now being used increasingly for biomaterials and tissue engineering applications. This book discusses the applications of silk for medical purposes with the first set of chapters covering the fundamentals and properties of silk for biomedical applications. Contributions in the second set of chapters look at a wide range of medical applications including tissue engineering and regenerative medicine, drug delivery and pharmaceutical applications.
Synopsis
Silk is increasingly being used as a biomaterial for tissue engineering applications, as well as sutures, due to its unique mechanical and chemical properties. Silk Biomaterials for Tissue Engineering and Regenerative Medicine discusses the properties of silk that make it useful for medical purposes and its applications in this area.
Part one introduces silk biomaterials, discussing their fundamentals and how they are processed, and considering different types of silk biomaterials. Part two focuses on the properties and behavior of silk biomaterials and the implications of this for their applications in biomedicine. These chapters focus on topics including biodegradation, bio-response to silk sericin, and capillary growth behavior in porous silk films. Finally, part three discusses the applications of silk biomaterials for tissue engineering, regenerative medicine, and biomedicine, with chapters on the use of silk biomaterials for vertebral, dental, dermal, and cardiac tissue engineering.
Silk Biomaterials for Tissue Engineering and Regenerative Medicine is an important resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics with an interest in the fields of biomaterials and tissue engineering.
- Discusses the properties and applications of silk for medical purposes
- Considers pharmaceutical and cosmeceutical applications
About the Author
Subhas Kundu is Professor of Biotechnology at the Indian Institute of Technology Kharagpur, India.
Table of Contents
Part 1 Fundamentals, processing and types of silk biomaterials: Introduction to silk biomaterials; Applications of silk biomaterials in tissue engineering and regenerative medicine; Processing of Bombyx mori silk for biomedical applications; Silk nanostructures based on natural and engineered self-assembly; Electropsun silk sericinnanofibers for biomedical applications; Silk fibroin microfiber and nanofiber scaffolds for tissue engineering and regeneration; Silk powder for regenerative medicine
Part 2 Properties and behaviour of silk biomaterials: Biochemical and biophysical properties of native Bombyx mori silk for tissue engineering applications; Structure and properties of spider and silkworm silk for tissue scaffolds; Types and properties of non-mulberry silk biomaterials for tissue engineering applications; Bio-response to silk sericin; Biodegradation behaviour of silk biomaterials; Capillary growth behaviour in porous silk films
Part 3 Tissue engineering, regenerative medicine and biomedical applications of silk biomaterials: Silk biomaterials for intervertebral disc (IVD) tissue engineering; Silk scaffolds for dental tissue engineering; Silk for cardiac tissue engineering; Silk for dermal tissue engineering; Silk scaffolds for 3D tumour modelling; Silk hydrogels for tissue engineering and dual drug delivery; Silk for pharmaceutical and cosmeceutical applications